Hydrogen-rich saline ameliorated LPS-induced acute lung injury via autophagy inhibition through the ROS/AMPK/mTOR pathway in mice

Over-activation of autophagy due to increased levels of reactive oxygen species is a key mechanism of lipopolysaccharide-induced acute lung injury. Hydrogen-rich saline, an antioxidant, has been proved to be an effective agent for the prevention of acute lung injury, but the underlying mechanism rem...

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Veröffentlicht in:	Experimental biology and medicine (Maywood, N.J.) N.J.), 2019-06, Vol.244 (9), p.721-727
Hauptverfasser:	Wang, Yong, Zhang, Jinghua, Bo, Jinsong, Wang, Xuefen, Zhu, Jingnan
Format:	Artikel
Sprache:	eng
Schlagworte:	Original Research
Online-Zugang:	Volltext
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