Mulberry Extract Attenuates Endothelial Dysfunction through the Regulation of Uncoupling Endothelial Nitric Oxide Synthase in High Fat Diet Rats

Dyslipidemia is associated with endothelial dysfunction, which is linked to nitric oxide (NO) biology. The coupling of endothelial NO synthase with cofactors is a major step for NO release. This study is aimed to investigate the vascular pharmacology effects of mulberry in rat thoracic aorta and hum...

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Veröffentlicht in:	Nutrients 2019-04, Vol.11 (5), p.978
Hauptverfasser:	Lee, Geum-Hwa, Hoang, The-Hiep, Jung, Eun-Soo, Jung, Su-Jin, Chae, Soo-Wan, Chae, Han-Jung
Format:	Artikel
Sprache:	eng
Schlagworte:	Abnormalities Anthocyanins Antioxidants Aorta Arteries Arteriosclerosis Atherosclerosis Bioavailability blood serum Contraction endothelial cells endothelial nitric oxide synthase Endothelium Flavonoids Fluorescein fruit extracts High fat diet humans hyperlipidemia keracyanin laboratory animals Lipids Low density lipoprotein mulberries Nitric oxide Nitric-oxide synthase Oxidation pharmacology Phenols phosphorylation Polarity protective effect rats reactive oxygen species Rodents
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