Characterization of a highly specific NQO1-activated near-infrared fluorescent probe and its application for in vivo tumor imaging

The Near-infrared Fluorescence (NIRF) molecular imaging of cancer is known to be superior in sensitivity, deeper penetration, and low phototoxicity compared to other imaging modalities. In view of an increased need for efficient and targeted imaging agents, we synthesized a NAD(P)H quinone oxidoredu...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Scientific reports 2019-06, Vol.9 (1), p.8577-8577, Article 8577
Hauptverfasser:	Punganuru, Surendra Reddy, Madala, Hanumantha Rao, Arutla, Viswanath, Zhang, Ruiwen, Srivenugopal, Kalkunte S.
Format:	Artikel
Sprache:	eng
Schlagworte:	13 13/1 13/109 13/51 14 14/34 14/69 38 38/89 59 631/67/2321 692/53/2421 A549 Cells Animal models Animals Cancer Female Flow Cytometry Fluorescence Fluorescence microscopy Fluorescent Dyes - chemistry Fluorescent indicators Heterografts Humanities and Social Sciences Humans I.R. radiation Lung cancer Lung carcinoma Mice Mice, Nude Microscopy, Fluorescence multidisciplinary NAD NAD(P)H Dehydrogenase (Quinone) - genetics NAD(P)H Dehydrogenase (Quinone) - metabolism Neoplasm Proteins - genetics Neoplasm Proteins - metabolism Neoplasm Transplantation Neoplasms, Experimental - diagnostic imaging Neoplasms, Experimental - genetics Neoplasms, Experimental - metabolism Phototoxicity Propionic acid Quinone oxidoreductase Science Science (multidisciplinary) siRNA Therapeutic applications Transfection Tumors Xenografts
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!