Crestal Bone Loss Around Submerged and Non-Submerged Dental Implants in Individuals with Type-2 Diabetes Mellitus: A 7-Year Prospective Clinical Study
Objective: In establishing an evidence-based rationale for the optimal use of implant therapy in patients with type 2 diabetes mellitus (T2DM), it is essential to first understand the impact of glycemic control on early healing and the success of dental implants. The objective of this study was to e...
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| Veröffentlicht in: | Medical Principles and Practice 2019-04, Vol.28 (1), p.75-81 |
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| creator | Al Zahrani, Saeed Al Mutairi, Abdullah A |
| description | Objective: In establishing an evidence-based rationale for the optimal use of implant therapy in patients with type 2 diabetes mellitus (T2DM), it is essential to first understand the impact of glycemic control on early healing and the success of dental implants. The objective of this study was to evaluate crestal bone loss (CBL) and stability around submerged and non-submerged dental implants in Saudi patients with well- and poorly controlled T2DM. Subject and Methods: Thirty-five patients with well-controlled T2DM (24 males and 11 females) and 32 poorly controlled T2DM patients (19 males and 13 females) were included. CBL was measured on digital radiographs; resonance frequency analysis (RFA) measurements were made for each implant at the time of fixture placement and at 3 months in both the groups. A p value less than 0.05 was considered statistically significant. Results: A total of 124 dental implants were placed. Mean RFA values between baseline and 3 months in poorly controlled T2DM patients was statistically significant (p = 0.048). CBL at first year (p = 0.047), second year (p = 0.041), third year (p = 0.046), and seventh year (p = 0.035) was significantly worse in poorly controlled T2DM. CBL around non-submerged dental implants showed statistically significant differences at all time-intervals (p < 0.05). Conclusion: Poorly controlled T2DM patients present worse peri-implant bone outcomes as compared to patients with well-controlled T2DM. We suggest that the predictability of successful dental implant therapy outcomes depends on the maintenance of optimal haemoglobin A1c levels. |
| doi_str_mv | 10.1159/000495111 |
| format | Article |
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The objective of this study was to evaluate crestal bone loss (CBL) and stability around submerged and non-submerged dental implants in Saudi patients with well- and poorly controlled T2DM. Subject and Methods: Thirty-five patients with well-controlled T2DM (24 males and 11 females) and 32 poorly controlled T2DM patients (19 males and 13 females) were included. CBL was measured on digital radiographs; resonance frequency analysis (RFA) measurements were made for each implant at the time of fixture placement and at 3 months in both the groups. A p value less than 0.05 was considered statistically significant. Results: A total of 124 dental implants were placed. Mean RFA values between baseline and 3 months in poorly controlled T2DM patients was statistically significant (p = 0.048). CBL at first year (p = 0.047), second year (p = 0.041), third year (p = 0.046), and seventh year (p = 0.035) was significantly worse in poorly controlled T2DM. CBL around non-submerged dental implants showed statistically significant differences at all time-intervals (p < 0.05). Conclusion: Poorly controlled T2DM patients present worse peri-implant bone outcomes as compared to patients with well-controlled T2DM. We suggest that the predictability of successful dental implant therapy outcomes depends on the maintenance of optimal haemoglobin A1c levels.</description><identifier>ISSN: 1011-7571</identifier><identifier>EISSN: 1423-0151</identifier><identifier>DOI: 10.1159/000495111</identifier><identifier>PMID: 30396170</identifier><language>eng</language><publisher>Basel, Switzerland: S. Karger AG</publisher><subject>Adult ; Aged ; Alveolar Bone Loss - complications ; Complications and side effects ; Cytokines ; Dental Implants ; Diabetes ; Diabetes mellitus ; Diabetes Mellitus, Type 2 - blood ; Diabetes Mellitus, Type 2 - complications ; Diabetes therapy ; Evidence-based medicine ; Female ; Glycated Hemoglobin A - analysis ; Glycosylated hemoglobin ; Hemoglobins ; Humans ; Hyperglycemia ; Male ; Mandibular Diseases - complications ; Mandibular Diseases - surgery ; Maxillary Diseases - complications ; Maxillary Diseases - surgery ; Middle Aged ; Oral hygiene ; Original Paper ; Patient outcomes ; Prospective Studies ; Saudi Arabia ; Success ; Surgeons ; Surveys and Questionnaires ; Transplants & implants ; Treatment Outcome ; Type 2 diabetes</subject><ispartof>Medical Principles and Practice, 2019-04, Vol.28 (1), p.75-81</ispartof><rights>2018 The Author(s) Published by S. Karger AG, Basel</rights><rights>2018 The Author(s) Published by S. Karger AG, Basel.</rights><rights>COPYRIGHT 2019 S. Karger AG</rights><rights>Copyright © 2018 by S. Karger AG, Basel 2018</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c519t-7d7a8b39d2d52c27813dc271908fd782c9fd7ad561185137ee0d75a79a817c43</citedby><cites>FETCH-LOGICAL-c519t-7d7a8b39d2d52c27813dc271908fd782c9fd7ad561185137ee0d75a79a817c43</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC6558320/pdf/$$EPDF$$P50$$Gpubmedcentral$$H</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC6558320/$$EHTML$$P50$$Gpubmedcentral$$H</linktohtml><link.rule.ids>230,314,723,776,780,860,881,27612,27901,27902,53766,53768</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/30396170$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Al Zahrani, Saeed</creatorcontrib><creatorcontrib>Al Mutairi, Abdullah A</creatorcontrib><title>Crestal Bone Loss Around Submerged and Non-Submerged Dental Implants in Individuals with Type-2 Diabetes Mellitus: A 7-Year Prospective Clinical Study</title><title>Medical Principles and Practice</title><addtitle>Med Princ Pract</addtitle><description>Objective: In establishing an evidence-based rationale for the optimal use of implant therapy in patients with type 2 diabetes mellitus (T2DM), it is essential to first understand the impact of glycemic control on early healing and the success of dental implants. The objective of this study was to evaluate crestal bone loss (CBL) and stability around submerged and non-submerged dental implants in Saudi patients with well- and poorly controlled T2DM. Subject and Methods: Thirty-five patients with well-controlled T2DM (24 males and 11 females) and 32 poorly controlled T2DM patients (19 males and 13 females) were included. CBL was measured on digital radiographs; resonance frequency analysis (RFA) measurements were made for each implant at the time of fixture placement and at 3 months in both the groups. A p value less than 0.05 was considered statistically significant. Results: A total of 124 dental implants were placed. Mean RFA values between baseline and 3 months in poorly controlled T2DM patients was statistically significant (p = 0.048). CBL at first year (p = 0.047), second year (p = 0.041), third year (p = 0.046), and seventh year (p = 0.035) was significantly worse in poorly controlled T2DM. CBL around non-submerged dental implants showed statistically significant differences at all time-intervals (p < 0.05). Conclusion: Poorly controlled T2DM patients present worse peri-implant bone outcomes as compared to patients with well-controlled T2DM. We suggest that the predictability of successful dental implant therapy outcomes depends on the maintenance of optimal haemoglobin A1c levels.</description><subject>Adult</subject><subject>Aged</subject><subject>Alveolar Bone Loss - complications</subject><subject>Complications and side effects</subject><subject>Cytokines</subject><subject>Dental Implants</subject><subject>Diabetes</subject><subject>Diabetes mellitus</subject><subject>Diabetes Mellitus, Type 2 - blood</subject><subject>Diabetes Mellitus, Type 2 - complications</subject><subject>Diabetes therapy</subject><subject>Evidence-based medicine</subject><subject>Female</subject><subject>Glycated Hemoglobin A - analysis</subject><subject>Glycosylated hemoglobin</subject><subject>Hemoglobins</subject><subject>Humans</subject><subject>Hyperglycemia</subject><subject>Male</subject><subject>Mandibular Diseases - complications</subject><subject>Mandibular Diseases - surgery</subject><subject>Maxillary Diseases - complications</subject><subject>Maxillary Diseases - surgery</subject><subject>Middle Aged</subject><subject>Oral hygiene</subject><subject>Original Paper</subject><subject>Patient outcomes</subject><subject>Prospective Studies</subject><subject>Saudi Arabia</subject><subject>Success</subject><subject>Surgeons</subject><subject>Surveys and Questionnaires</subject><subject>Transplants & implants</subject><subject>Treatment Outcome</subject><subject>Type 2 diabetes</subject><issn>1011-7571</issn><issn>1423-0151</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2019</creationdate><recordtype>article</recordtype><sourceid>M--</sourceid><sourceid>EIF</sourceid><sourceid>BENPR</sourceid><recordid>eNptkk1vEzEQhlcIREvhwB0hS1zgsMWzjuM1B6SQ8hEphUjNhZPl2N7WZWMv9m5Q_gi_l4kSUkDIh_F6n3nH73iK4inQcwAuX1NKR5IDwL3iFEYVKylwuI97ClAKLuCkeJTzLWI1Y_RhccIok2MQ9LT4OU0u97ol72JwZB5zJpMUh2DJ1bBau3TtLNH49TmG8u7kwoVdzmzdtTr0mfhAZsH6jbeDbjP54fsbstx2rqzIhdcr17tMLl3b-n7Ib8iEiPKr04ksUsydM73fODJtffAGRa_6wW4fFw8aVHJPDvGsWH54v5x-KudfPs6mk3lpOMi-FFboesWkrSyvTCVqYBYDSFo3VtSVkRi05WOAmgMTzlEruBZS1yDMiJ0Vb_ey3c6aNWgr6VZ1ya912qqovfr7T_A36jpu1JjzmlUUBV4eBFL8PmAn1dpng051cHHIqgJsNQVZ72q9-Ae9jUMK6E5VO4SOQEikzvfUtW6d8qGJWNfgsm7tDb5R4_F8wqUQwCs2xoRX-wSDzczJNcfbA1W76VDH6UD2-Z92j-Tvcbi74zeN75yOwOVisZdQnW2QevZf6lDlF_eiyW8</recordid><startdate>20190401</startdate><enddate>20190401</enddate><creator>Al Zahrani, Saeed</creator><creator>Al Mutairi, Abdullah A</creator><general>S. Karger AG</general><scope>M--</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>IAO</scope><scope>3V.</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9.</scope><scope>M0S</scope><scope>M1P</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>20190401</creationdate><title>Crestal Bone Loss Around Submerged and Non-Submerged Dental Implants in Individuals with Type-2 Diabetes Mellitus: A 7-Year Prospective Clinical Study</title><author>Al Zahrani, Saeed ; Al Mutairi, Abdullah A</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c519t-7d7a8b39d2d52c27813dc271908fd782c9fd7ad561185137ee0d75a79a817c43</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2019</creationdate><topic>Adult</topic><topic>Aged</topic><topic>Alveolar Bone Loss - complications</topic><topic>Complications and side effects</topic><topic>Cytokines</topic><topic>Dental Implants</topic><topic>Diabetes</topic><topic>Diabetes mellitus</topic><topic>Diabetes Mellitus, Type 2 - blood</topic><topic>Diabetes Mellitus, Type 2 - complications</topic><topic>Diabetes therapy</topic><topic>Evidence-based medicine</topic><topic>Female</topic><topic>Glycated Hemoglobin A - analysis</topic><topic>Glycosylated hemoglobin</topic><topic>Hemoglobins</topic><topic>Humans</topic><topic>Hyperglycemia</topic><topic>Male</topic><topic>Mandibular Diseases - complications</topic><topic>Mandibular Diseases - surgery</topic><topic>Maxillary Diseases - complications</topic><topic>Maxillary Diseases - surgery</topic><topic>Middle Aged</topic><topic>Oral hygiene</topic><topic>Original Paper</topic><topic>Patient outcomes</topic><topic>Prospective Studies</topic><topic>Saudi Arabia</topic><topic>Success</topic><topic>Surgeons</topic><topic>Surveys and Questionnaires</topic><topic>Transplants & implants</topic><topic>Treatment Outcome</topic><topic>Type 2 diabetes</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Al Zahrani, Saeed</creatorcontrib><creatorcontrib>Al Mutairi, Abdullah A</creatorcontrib><collection>Karger Open Access</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Gale Academic OneFile</collection><collection>ProQuest Central (Corporate)</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Medical Principles and Practice</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Al Zahrani, Saeed</au><au>Al Mutairi, Abdullah A</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Crestal Bone Loss Around Submerged and Non-Submerged Dental Implants in Individuals with Type-2 Diabetes Mellitus: A 7-Year Prospective Clinical Study</atitle><jtitle>Medical Principles and Practice</jtitle><addtitle>Med Princ Pract</addtitle><date>2019-04-01</date><risdate>2019</risdate><volume>28</volume><issue>1</issue><spage>75</spage><epage>81</epage><pages>75-81</pages><issn>1011-7571</issn><eissn>1423-0151</eissn><abstract>Objective: In establishing an evidence-based rationale for the optimal use of implant therapy in patients with type 2 diabetes mellitus (T2DM), it is essential to first understand the impact of glycemic control on early healing and the success of dental implants. The objective of this study was to evaluate crestal bone loss (CBL) and stability around submerged and non-submerged dental implants in Saudi patients with well- and poorly controlled T2DM. Subject and Methods: Thirty-five patients with well-controlled T2DM (24 males and 11 females) and 32 poorly controlled T2DM patients (19 males and 13 females) were included. CBL was measured on digital radiographs; resonance frequency analysis (RFA) measurements were made for each implant at the time of fixture placement and at 3 months in both the groups. A p value less than 0.05 was considered statistically significant. Results: A total of 124 dental implants were placed. Mean RFA values between baseline and 3 months in poorly controlled T2DM patients was statistically significant (p = 0.048). CBL at first year (p = 0.047), second year (p = 0.041), third year (p = 0.046), and seventh year (p = 0.035) was significantly worse in poorly controlled T2DM. CBL around non-submerged dental implants showed statistically significant differences at all time-intervals (p < 0.05). Conclusion: Poorly controlled T2DM patients present worse peri-implant bone outcomes as compared to patients with well-controlled T2DM. We suggest that the predictability of successful dental implant therapy outcomes depends on the maintenance of optimal haemoglobin A1c levels.</abstract><cop>Basel, Switzerland</cop><pub>S. Karger AG</pub><pmid>30396170</pmid><doi>10.1159/000495111</doi><tpages>7</tpages><oa>free_for_read</oa></addata></record> |
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| source | MEDLINE; DOAJ Directory of Open Access Journals; EZB-FREE-00999 freely available EZB journals; PubMed Central; Karger Open Access |
| subjects | Adult Aged Alveolar Bone Loss - complications Complications and side effects Cytokines Dental Implants Diabetes Diabetes mellitus Diabetes Mellitus, Type 2 - blood Diabetes Mellitus, Type 2 - complications Diabetes therapy Evidence-based medicine Female Glycated Hemoglobin A - analysis Glycosylated hemoglobin Hemoglobins Humans Hyperglycemia Male Mandibular Diseases - complications Mandibular Diseases - surgery Maxillary Diseases - complications Maxillary Diseases - surgery Middle Aged Oral hygiene Original Paper Patient outcomes Prospective Studies Saudi Arabia Success Surgeons Surveys and Questionnaires Transplants & implants Treatment Outcome Type 2 diabetes |
| title | Crestal Bone Loss Around Submerged and Non-Submerged Dental Implants in Individuals with Type-2 Diabetes Mellitus: A 7-Year Prospective Clinical Study |
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