Reciprocal cortical activation patterns during incisal and molar biting correlated with bite force levels: an fMRI study
In humans, the incisors and molars have distinct functions during mastication, analogous to the two main types of handgrip, the precision and power grips. In the present study, we investigated cortical activation and masticatory muscle activity during incisal and molar biting via simultaneous functi...
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| Veröffentlicht in: | Scientific reports 2019-06, Vol.9 (1), p.8419-8419, Article 8419 |
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| creator | Yoshizawa, Hideyuki Miyamoto, Jun J. Hanakawa, Takashi Shitara, Hitoshi Honda, Manabu Moriyama, Keiji |
| description | In humans, the incisors and molars have distinct functions during mastication, analogous to the two main types of handgrip, the precision and power grips. In the present study, we investigated cortical activation and masticatory muscle activity during incisal and molar biting via simultaneous functional magnetic resonance imaging and electromyogram (EMG) recordings. We conducted recordings in 15 healthy adult participants while they performed incisal and molar biting tasks at three step-wise force levels using two custom-made splints. Regarding the results of the ROI analysis, we found a significantly stronger positive linear correlation between the blood oxygenation level dependent signal and EMG activity during molar biting than incisal biting, which was particularly prominent in the primary sensorimotor cortex and the cerebellum. We also found a significantly stronger negative linear correlation during incisal biting than molar biting, which was particularly prominent in the rostral cingulate motor area, superior frontal gyrus, and caudate nucleus. These findings indicate that molar biting enables powerful chewing: brain activity in several brain areas related to motor function was increased with increasing bite force levels, while incisal biting enables fine motor control: brain activity in several brain areas related to motor control was increased with reduced bite force levels. |
| doi_str_mv | 10.1038/s41598-019-44846-4 |
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In the present study, we investigated cortical activation and masticatory muscle activity during incisal and molar biting via simultaneous functional magnetic resonance imaging and electromyogram (EMG) recordings. We conducted recordings in 15 healthy adult participants while they performed incisal and molar biting tasks at three step-wise force levels using two custom-made splints. Regarding the results of the ROI analysis, we found a significantly stronger positive linear correlation between the blood oxygenation level dependent signal and EMG activity during molar biting than incisal biting, which was particularly prominent in the primary sensorimotor cortex and the cerebellum. We also found a significantly stronger negative linear correlation during incisal biting than molar biting, which was particularly prominent in the rostral cingulate motor area, superior frontal gyrus, and caudate nucleus. These findings indicate that molar biting enables powerful chewing: brain activity in several brain areas related to motor function was increased with increasing bite force levels, while incisal biting enables fine motor control: brain activity in several brain areas related to motor control was increased with reduced bite force levels.</description><identifier>ISSN: 2045-2322</identifier><identifier>EISSN: 2045-2322</identifier><identifier>DOI: 10.1038/s41598-019-44846-4</identifier><identifier>PMID: 31182743</identifier><language>eng</language><publisher>London: Nature Publishing Group UK</publisher><subject>59/36 ; 631/378/2632 ; 692/698/3008 ; Adult ; Behavior ; Bite Force ; Biting ; Brain Mapping ; Caudate nucleus ; Cerebellum ; Cerebral Cortex - diagnostic imaging ; Cerebral Cortex - physiology ; Chewing ; Electromyography ; Female ; Frontal gyrus ; Functional magnetic resonance imaging ; Humanities and Social Sciences ; Humans ; Incisor - physiology ; Incisors ; Magnetic Resonance Imaging ; Male ; Mastication ; Mastication - physiology ; Middle Aged ; Molar - physiology ; Motor task performance ; Mouth ; multidisciplinary ; Muscle function ; Neuroimaging ; Oxygenation ; Power ; Science ; Science (multidisciplinary) ; Somatosensory cortex ; Teeth</subject><ispartof>Scientific reports, 2019-06, Vol.9 (1), p.8419-8419, Article 8419</ispartof><rights>The Author(s) 2019</rights><rights>The Author(s) 2019. 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In the present study, we investigated cortical activation and masticatory muscle activity during incisal and molar biting via simultaneous functional magnetic resonance imaging and electromyogram (EMG) recordings. We conducted recordings in 15 healthy adult participants while they performed incisal and molar biting tasks at three step-wise force levels using two custom-made splints. Regarding the results of the ROI analysis, we found a significantly stronger positive linear correlation between the blood oxygenation level dependent signal and EMG activity during molar biting than incisal biting, which was particularly prominent in the primary sensorimotor cortex and the cerebellum. We also found a significantly stronger negative linear correlation during incisal biting than molar biting, which was particularly prominent in the rostral cingulate motor area, superior frontal gyrus, and caudate nucleus. These findings indicate that molar biting enables powerful chewing: brain activity in several brain areas related to motor function was increased with increasing bite force levels, while incisal biting enables fine motor control: brain activity in several brain areas related to motor control was increased with reduced bite force levels.</description><subject>59/36</subject><subject>631/378/2632</subject><subject>692/698/3008</subject><subject>Adult</subject><subject>Behavior</subject><subject>Bite Force</subject><subject>Biting</subject><subject>Brain Mapping</subject><subject>Caudate nucleus</subject><subject>Cerebellum</subject><subject>Cerebral Cortex - diagnostic imaging</subject><subject>Cerebral Cortex - physiology</subject><subject>Chewing</subject><subject>Electromyography</subject><subject>Female</subject><subject>Frontal gyrus</subject><subject>Functional magnetic resonance imaging</subject><subject>Humanities and Social Sciences</subject><subject>Humans</subject><subject>Incisor - 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Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Scientific reports</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Yoshizawa, Hideyuki</au><au>Miyamoto, Jun J.</au><au>Hanakawa, Takashi</au><au>Shitara, Hitoshi</au><au>Honda, Manabu</au><au>Moriyama, Keiji</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Reciprocal cortical activation patterns during incisal and molar biting correlated with bite force levels: an fMRI study</atitle><jtitle>Scientific reports</jtitle><stitle>Sci Rep</stitle><addtitle>Sci Rep</addtitle><date>2019-06-10</date><risdate>2019</risdate><volume>9</volume><issue>1</issue><spage>8419</spage><epage>8419</epage><pages>8419-8419</pages><artnum>8419</artnum><issn>2045-2322</issn><eissn>2045-2322</eissn><abstract>In humans, the incisors and molars have distinct functions during mastication, analogous to the two main types of handgrip, the precision and power grips. In the present study, we investigated cortical activation and masticatory muscle activity during incisal and molar biting via simultaneous functional magnetic resonance imaging and electromyogram (EMG) recordings. We conducted recordings in 15 healthy adult participants while they performed incisal and molar biting tasks at three step-wise force levels using two custom-made splints. Regarding the results of the ROI analysis, we found a significantly stronger positive linear correlation between the blood oxygenation level dependent signal and EMG activity during molar biting than incisal biting, which was particularly prominent in the primary sensorimotor cortex and the cerebellum. We also found a significantly stronger negative linear correlation during incisal biting than molar biting, which was particularly prominent in the rostral cingulate motor area, superior frontal gyrus, and caudate nucleus. These findings indicate that molar biting enables powerful chewing: brain activity in several brain areas related to motor function was increased with increasing bite force levels, while incisal biting enables fine motor control: brain activity in several brain areas related to motor control was increased with reduced bite force levels.</abstract><cop>London</cop><pub>Nature Publishing Group UK</pub><pmid>31182743</pmid><doi>10.1038/s41598-019-44846-4</doi><tpages>1</tpages><orcidid>https://orcid.org/0000-0003-4166-4885</orcidid><orcidid>https://orcid.org/0000-0003-3547-0718</orcidid><oa>free_for_read</oa></addata></record> |
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| subjects | 59/36 631/378/2632 692/698/3008 Adult Behavior Bite Force Biting Brain Mapping Caudate nucleus Cerebellum Cerebral Cortex - diagnostic imaging Cerebral Cortex - physiology Chewing Electromyography Female Frontal gyrus Functional magnetic resonance imaging Humanities and Social Sciences Humans Incisor - physiology Incisors Magnetic Resonance Imaging Male Mastication Mastication - physiology Middle Aged Molar - physiology Motor task performance Mouth multidisciplinary Muscle function Neuroimaging Oxygenation Power Science Science (multidisciplinary) Somatosensory cortex Teeth |
| title | Reciprocal cortical activation patterns during incisal and molar biting correlated with bite force levels: an fMRI study |
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