Acute adverse events in cardiac MR imaging with gadolinium-based contrast agents: results from the European Society of Cardiovascular Radiology (ESCR) MRCT Registry in 72,839 patients
Objectives To assess the incidence of acute adverse events (AAEs) in gadolinium-enhanced cardiac magnetic resonance (CMR) imaging. Methods Gadolinium-based contrast agent (GBCA)–enhanced CMR data from the multinational, multicenter European Society of Cardiovascular Radiology MRCT Registry was inclu...
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| Veröffentlicht in: | European radiology 2019-07, Vol.29 (7), p.3686-3695 |
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| creator | Uhlig, Johannes Lücke, Christian Vliegenthart, Rozemarijn Loewe, Christian Grothoff, Matthias Schuster, Andreas Lurz, Philipp Jacquier, Alexis Francone, Marco Zapf, Antonia Schülke, Christoph May, Matthias Stefan Bremerich, Jens Lotz, Joachim Gutberlet, Matthias |
| description | Objectives
To assess the incidence of acute adverse events (AAEs) in gadolinium-enhanced cardiac magnetic resonance (CMR) imaging.
Methods
Gadolinium-based contrast agent (GBCA)–enhanced CMR data from the multinational, multicenter European Society of Cardiovascular Radiology MRCT Registry was included. AAE severity was classified according to the American College of Radiology Manual on Contrast Media (mild, moderate, severe). Multivariable generalized linear mixed effect models were used to assess the likelihood of AAEs in various GBCA, adjusting for pharmacological stressor, main indications (i.e., suspected or known coronary artery disease or myocarditis), age, sex, and submitting center as a random effect.
Results
In the study population of 72,839 GBCA-enhanced CMRs, a total of 260 AAEs were reported (0.36%), with a minority of severe AAEs (
n
= 24, 0.033%). Allergic-like AAEs were less likely than physiologic AAEs (29% versus 71%). Patients without pharmacological stress imaging had a lower AAE rate (0.22%) compared to stress imaging (0.75%), with the highest AAE rates for regadenoson (2.95%). AAE rates also varied by GBCA subtype (overall
p
|
| doi_str_mv | 10.1007/s00330-019-06171-2 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6554260</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2217185175</sourcerecordid><originalsourceid>FETCH-LOGICAL-c508t-5ea035c0d0e90f5d4acc475e325a1e309243742d917ad3d01480f8e252489f083</originalsourceid><addsrcrecordid>eNp9UktvEzEQXiEQTQt_gAOyxIVKLIxf--CAFEWBIgUhpeVsud7ZjavNOrW9Qfll_Xt4SSmPAyfLnu8xM_6y7AWFtxSgfBcAOIccaJ1DQUuas0fZjArOcgqVeJzNoOZVXta1OMlOQ7gBgJqK8ml2wikIKotilt3NzRiR6GaPPiDBPQ4xEDsQo31jtSFf1sRudWeHjny3cUM63bjeDnbc5tc6YEOMG6LXIRLdTdz3xGMY-yTSerclcYNkOXq3Qz2QS2csxgNxLVlM8m6vgxl77clap1vvugN5vbxcrM-T7eKKrLGzIfrD1E_J3lS8Jjsd7WTzLHvS6j7g8_vzLPv2cXm1uMhXXz99XsxXuZFQxVyiBi4NNIA1tLIR2hhRSuRMaoocaiZ4KVhT01I3vAEqKmgrZJKJqm6h4mfZh6PubrzeYmNwGrZXO5-W4g_Kaav-rgx2ozq3V4WUghWQBM6PApt_aBfzlZreUn9VXRRyTxP21b2Zd7cjhqhu3OiHNJ9iLH1wJWkpE4odUca7EDy2D7IU1BQMdQyGSsFQP4OhWCK9_HOOB8qvJCQAPwJCKg0d-t_e_5H9AeN8xHY</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2217185175</pqid></control><display><type>article</type><title>Acute adverse events in cardiac MR imaging with gadolinium-based contrast agents: results from the European Society of Cardiovascular Radiology (ESCR) MRCT Registry in 72,839 patients</title><source>MEDLINE</source><source>SpringerLink Journals - AutoHoldings</source><creator>Uhlig, Johannes ; Lücke, Christian ; Vliegenthart, Rozemarijn ; Loewe, Christian ; Grothoff, Matthias ; Schuster, Andreas ; Lurz, Philipp ; Jacquier, Alexis ; Francone, Marco ; Zapf, Antonia ; Schülke, Christoph ; May, Matthias Stefan ; Bremerich, Jens ; Lotz, Joachim ; Gutberlet, Matthias</creator><creatorcontrib>Uhlig, Johannes ; Lücke, Christian ; Vliegenthart, Rozemarijn ; Loewe, Christian ; Grothoff, Matthias ; Schuster, Andreas ; Lurz, Philipp ; Jacquier, Alexis ; Francone, Marco ; Zapf, Antonia ; Schülke, Christoph ; May, Matthias Stefan ; Bremerich, Jens ; Lotz, Joachim ; Gutberlet, Matthias ; Daniel Thomas ; ESCR MRCT Registry contributors ; the ESCR MRCT Registry contributors</creatorcontrib><description>Objectives
To assess the incidence of acute adverse events (AAEs) in gadolinium-enhanced cardiac magnetic resonance (CMR) imaging.
Methods
Gadolinium-based contrast agent (GBCA)–enhanced CMR data from the multinational, multicenter European Society of Cardiovascular Radiology MRCT Registry was included. AAE severity was classified according to the American College of Radiology Manual on Contrast Media (mild, moderate, severe). Multivariable generalized linear mixed effect models were used to assess the likelihood of AAEs in various GBCA, adjusting for pharmacological stressor, main indications (i.e., suspected or known coronary artery disease or myocarditis), age, sex, and submitting center as a random effect.
Results
In the study population of 72,839 GBCA-enhanced CMRs, a total of 260 AAEs were reported (0.36%), with a minority of severe AAEs (
n
= 24, 0.033%). Allergic-like AAEs were less likely than physiologic AAEs (29% versus 71%). Patients without pharmacological stress imaging had a lower AAE rate (0.22%) compared to stress imaging (0.75%), with the highest AAE rates for regadenoson (2.95%). AAE rates also varied by GBCA subtype (overall
p
< 0.001). There was significant interaction between GBCA and pharmacological stressor (interaction
p
= 0.025), with AAE rates ranging between 0 and 10% for certain GBCA/stressor combinations. There was further marginal evidence that higher GBCA volume was associated with higher AAE incidence (OR = 1.02,
p
= 0.05).
Conclusion
GBCA-enhanced CMR imaging demonstrates low AAE rates comparable to those of other body regions. AAE likelihood correlates with GBCA subtype, pharmacological stressor, and imaging indication. Intravenous fluid administration in patients with cardiac impairment might contribute to these findings.
Key Points
• Acute adverse event rates in cardiac magnetic resonance (CMR) imaging with gadolinium-based contrast agents (GBCAs) are low (0.36%), especially for severe adverse events (0.033%).
• Mild and moderate adverse events are more frequent during stress CMR imaging.
• Physiologic AAEs are more common than allergic AAEs in CMR imaging.</description><identifier>ISSN: 0938-7994</identifier><identifier>EISSN: 1432-1084</identifier><identifier>DOI: 10.1007/s00330-019-06171-2</identifier><identifier>PMID: 31041566</identifier><language>eng</language><publisher>Berlin/Heidelberg: Springer Berlin Heidelberg</publisher><subject>Acute Disease ; Administration, Intravenous ; Cardiac ; Cardiovascular disease ; Cardiovascular Diseases - diagnosis ; Contrast agents ; Contrast media ; Coronary artery ; Coronary artery disease ; Diagnostic Radiology ; Drug-Related Side Effects and Adverse Reactions - epidemiology ; Drug-Related Side Effects and Adverse Reactions - etiology ; Europe - epidemiology ; Female ; Gadolinium ; Heart diseases ; Humans ; Imaging ; Incidence ; Internal Medicine ; Interventional Radiology ; Intravenous administration ; Life Sciences ; Magnetic resonance imaging ; Magnetic Resonance Imaging, Cine - adverse effects ; Magnetic Resonance Imaging, Cine - methods ; Male ; Medical imaging ; Medicine ; Medicine & Public Health ; Middle Aged ; Myocarditis ; Neuroradiology ; Organometallic Compounds - administration & dosage ; Organometallic Compounds - adverse effects ; Pharmacology ; Population studies ; Radiology ; Registries ; Resonance ; Retrospective Studies ; Societies, Medical ; Ultrasound</subject><ispartof>European radiology, 2019-07, Vol.29 (7), p.3686-3695</ispartof><rights>The Author(s) 2019</rights><rights>European Radiology is a copyright of Springer, (2019). All Rights Reserved. © 2019. This work is published under http://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><rights>Distributed under a Creative Commons Attribution 4.0 International License</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c508t-5ea035c0d0e90f5d4acc475e325a1e309243742d917ad3d01480f8e252489f083</citedby><cites>FETCH-LOGICAL-c508t-5ea035c0d0e90f5d4acc475e325a1e309243742d917ad3d01480f8e252489f083</cites><orcidid>0000-0003-4879-0438 ; 0000-0003-0297-7942</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1007/s00330-019-06171-2$$EPDF$$P50$$Gspringer$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1007/s00330-019-06171-2$$EHTML$$P50$$Gspringer$$Hfree_for_read</linktohtml><link.rule.ids>230,314,776,780,881,27901,27902,41464,42533,51294</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/31041566$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink><backlink>$$Uhttps://hal.science/hal-03589665$$DView record in HAL$$Hfree_for_read</backlink></links><search><creatorcontrib>Uhlig, Johannes</creatorcontrib><creatorcontrib>Lücke, Christian</creatorcontrib><creatorcontrib>Vliegenthart, Rozemarijn</creatorcontrib><creatorcontrib>Loewe, Christian</creatorcontrib><creatorcontrib>Grothoff, Matthias</creatorcontrib><creatorcontrib>Schuster, Andreas</creatorcontrib><creatorcontrib>Lurz, Philipp</creatorcontrib><creatorcontrib>Jacquier, Alexis</creatorcontrib><creatorcontrib>Francone, Marco</creatorcontrib><creatorcontrib>Zapf, Antonia</creatorcontrib><creatorcontrib>Schülke, Christoph</creatorcontrib><creatorcontrib>May, Matthias Stefan</creatorcontrib><creatorcontrib>Bremerich, Jens</creatorcontrib><creatorcontrib>Lotz, Joachim</creatorcontrib><creatorcontrib>Gutberlet, Matthias</creatorcontrib><creatorcontrib>Daniel Thomas</creatorcontrib><creatorcontrib>ESCR MRCT Registry contributors</creatorcontrib><creatorcontrib>the ESCR MRCT Registry contributors</creatorcontrib><title>Acute adverse events in cardiac MR imaging with gadolinium-based contrast agents: results from the European Society of Cardiovascular Radiology (ESCR) MRCT Registry in 72,839 patients</title><title>European radiology</title><addtitle>Eur Radiol</addtitle><addtitle>Eur Radiol</addtitle><description>Objectives
To assess the incidence of acute adverse events (AAEs) in gadolinium-enhanced cardiac magnetic resonance (CMR) imaging.
Methods
Gadolinium-based contrast agent (GBCA)–enhanced CMR data from the multinational, multicenter European Society of Cardiovascular Radiology MRCT Registry was included. AAE severity was classified according to the American College of Radiology Manual on Contrast Media (mild, moderate, severe). Multivariable generalized linear mixed effect models were used to assess the likelihood of AAEs in various GBCA, adjusting for pharmacological stressor, main indications (i.e., suspected or known coronary artery disease or myocarditis), age, sex, and submitting center as a random effect.
Results
In the study population of 72,839 GBCA-enhanced CMRs, a total of 260 AAEs were reported (0.36%), with a minority of severe AAEs (
n
= 24, 0.033%). Allergic-like AAEs were less likely than physiologic AAEs (29% versus 71%). Patients without pharmacological stress imaging had a lower AAE rate (0.22%) compared to stress imaging (0.75%), with the highest AAE rates for regadenoson (2.95%). AAE rates also varied by GBCA subtype (overall
p
< 0.001). There was significant interaction between GBCA and pharmacological stressor (interaction
p
= 0.025), with AAE rates ranging between 0 and 10% for certain GBCA/stressor combinations. There was further marginal evidence that higher GBCA volume was associated with higher AAE incidence (OR = 1.02,
p
= 0.05).
Conclusion
GBCA-enhanced CMR imaging demonstrates low AAE rates comparable to those of other body regions. AAE likelihood correlates with GBCA subtype, pharmacological stressor, and imaging indication. Intravenous fluid administration in patients with cardiac impairment might contribute to these findings.
Key Points
• Acute adverse event rates in cardiac magnetic resonance (CMR) imaging with gadolinium-based contrast agents (GBCAs) are low (0.36%), especially for severe adverse events (0.033%).
• Mild and moderate adverse events are more frequent during stress CMR imaging.
• Physiologic AAEs are more common than allergic AAEs in CMR imaging.</description><subject>Acute Disease</subject><subject>Administration, Intravenous</subject><subject>Cardiac</subject><subject>Cardiovascular disease</subject><subject>Cardiovascular Diseases - diagnosis</subject><subject>Contrast agents</subject><subject>Contrast media</subject><subject>Coronary artery</subject><subject>Coronary artery disease</subject><subject>Diagnostic Radiology</subject><subject>Drug-Related Side Effects and Adverse Reactions - epidemiology</subject><subject>Drug-Related Side Effects and Adverse Reactions - etiology</subject><subject>Europe - epidemiology</subject><subject>Female</subject><subject>Gadolinium</subject><subject>Heart diseases</subject><subject>Humans</subject><subject>Imaging</subject><subject>Incidence</subject><subject>Internal Medicine</subject><subject>Interventional Radiology</subject><subject>Intravenous administration</subject><subject>Life Sciences</subject><subject>Magnetic resonance imaging</subject><subject>Magnetic Resonance Imaging, Cine - adverse effects</subject><subject>Magnetic Resonance Imaging, Cine - methods</subject><subject>Male</subject><subject>Medical imaging</subject><subject>Medicine</subject><subject>Medicine & Public Health</subject><subject>Middle Aged</subject><subject>Myocarditis</subject><subject>Neuroradiology</subject><subject>Organometallic Compounds - administration & dosage</subject><subject>Organometallic Compounds - adverse effects</subject><subject>Pharmacology</subject><subject>Population studies</subject><subject>Radiology</subject><subject>Registries</subject><subject>Resonance</subject><subject>Retrospective Studies</subject><subject>Societies, 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adverse events in cardiac MR imaging with gadolinium-based contrast agents: results from the European Society of Cardiovascular Radiology (ESCR) MRCT Registry in 72,839 patients</title><author>Uhlig, Johannes ; Lücke, Christian ; Vliegenthart, Rozemarijn ; Loewe, Christian ; Grothoff, Matthias ; Schuster, Andreas ; Lurz, Philipp ; Jacquier, Alexis ; Francone, Marco ; Zapf, Antonia ; Schülke, Christoph ; May, Matthias Stefan ; Bremerich, Jens ; Lotz, Joachim ; Gutberlet, Matthias</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c508t-5ea035c0d0e90f5d4acc475e325a1e309243742d917ad3d01480f8e252489f083</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2019</creationdate><topic>Acute Disease</topic><topic>Administration, Intravenous</topic><topic>Cardiac</topic><topic>Cardiovascular disease</topic><topic>Cardiovascular Diseases - diagnosis</topic><topic>Contrast agents</topic><topic>Contrast media</topic><topic>Coronary artery</topic><topic>Coronary artery disease</topic><topic>Diagnostic Radiology</topic><topic>Drug-Related Side Effects and Adverse Reactions - epidemiology</topic><topic>Drug-Related Side Effects and Adverse Reactions - etiology</topic><topic>Europe - epidemiology</topic><topic>Female</topic><topic>Gadolinium</topic><topic>Heart diseases</topic><topic>Humans</topic><topic>Imaging</topic><topic>Incidence</topic><topic>Internal Medicine</topic><topic>Interventional Radiology</topic><topic>Intravenous administration</topic><topic>Life Sciences</topic><topic>Magnetic resonance imaging</topic><topic>Magnetic Resonance Imaging, Cine - adverse effects</topic><topic>Magnetic Resonance Imaging, Cine - methods</topic><topic>Male</topic><topic>Medical imaging</topic><topic>Medicine</topic><topic>Medicine & Public Health</topic><topic>Middle Aged</topic><topic>Myocarditis</topic><topic>Neuroradiology</topic><topic>Organometallic Compounds - administration & dosage</topic><topic>Organometallic Compounds - adverse effects</topic><topic>Pharmacology</topic><topic>Population studies</topic><topic>Radiology</topic><topic>Registries</topic><topic>Resonance</topic><topic>Retrospective Studies</topic><topic>Societies, Medical</topic><topic>Ultrasound</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Uhlig, Johannes</creatorcontrib><creatorcontrib>Lücke, Christian</creatorcontrib><creatorcontrib>Vliegenthart, Rozemarijn</creatorcontrib><creatorcontrib>Loewe, Christian</creatorcontrib><creatorcontrib>Grothoff, Matthias</creatorcontrib><creatorcontrib>Schuster, Andreas</creatorcontrib><creatorcontrib>Lurz, Philipp</creatorcontrib><creatorcontrib>Jacquier, Alexis</creatorcontrib><creatorcontrib>Francone, Marco</creatorcontrib><creatorcontrib>Zapf, Antonia</creatorcontrib><creatorcontrib>Schülke, Christoph</creatorcontrib><creatorcontrib>May, Matthias Stefan</creatorcontrib><creatorcontrib>Bremerich, Jens</creatorcontrib><creatorcontrib>Lotz, Joachim</creatorcontrib><creatorcontrib>Gutberlet, Matthias</creatorcontrib><creatorcontrib>Daniel Thomas</creatorcontrib><creatorcontrib>ESCR MRCT Registry contributors</creatorcontrib><creatorcontrib>the ESCR MRCT Registry contributors</creatorcontrib><collection>Springer Nature OA Free Journals</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Biotechnology Research Abstracts</collection><collection>Nursing & Allied Health Database</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>ProQuest Pharma 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(New)</collection><collection>ProQuest Health & Medical Research Collection</collection><collection>ProQuest One Academic Middle East (New)</collection><collection>ProQuest One Health & Nursing</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Applied & Life Sciences</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>Hyper Article en Ligne (HAL)</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>European radiology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Uhlig, Johannes</au><au>Lücke, Christian</au><au>Vliegenthart, Rozemarijn</au><au>Loewe, Christian</au><au>Grothoff, Matthias</au><au>Schuster, Andreas</au><au>Lurz, Philipp</au><au>Jacquier, Alexis</au><au>Francone, Marco</au><au>Zapf, Antonia</au><au>Schülke, Christoph</au><au>May, Matthias Stefan</au><au>Bremerich, Jens</au><au>Lotz, Joachim</au><au>Gutberlet, Matthias</au><aucorp>Daniel Thomas</aucorp><aucorp>ESCR MRCT Registry contributors</aucorp><aucorp>the ESCR MRCT Registry contributors</aucorp><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Acute adverse events in cardiac MR imaging with gadolinium-based contrast agents: results from the European Society of Cardiovascular Radiology (ESCR) MRCT Registry in 72,839 patients</atitle><jtitle>European radiology</jtitle><stitle>Eur Radiol</stitle><addtitle>Eur Radiol</addtitle><date>2019-07-01</date><risdate>2019</risdate><volume>29</volume><issue>7</issue><spage>3686</spage><epage>3695</epage><pages>3686-3695</pages><issn>0938-7994</issn><eissn>1432-1084</eissn><abstract>Objectives
To assess the incidence of acute adverse events (AAEs) in gadolinium-enhanced cardiac magnetic resonance (CMR) imaging.
Methods
Gadolinium-based contrast agent (GBCA)–enhanced CMR data from the multinational, multicenter European Society of Cardiovascular Radiology MRCT Registry was included. AAE severity was classified according to the American College of Radiology Manual on Contrast Media (mild, moderate, severe). Multivariable generalized linear mixed effect models were used to assess the likelihood of AAEs in various GBCA, adjusting for pharmacological stressor, main indications (i.e., suspected or known coronary artery disease or myocarditis), age, sex, and submitting center as a random effect.
Results
In the study population of 72,839 GBCA-enhanced CMRs, a total of 260 AAEs were reported (0.36%), with a minority of severe AAEs (
n
= 24, 0.033%). Allergic-like AAEs were less likely than physiologic AAEs (29% versus 71%). Patients without pharmacological stress imaging had a lower AAE rate (0.22%) compared to stress imaging (0.75%), with the highest AAE rates for regadenoson (2.95%). AAE rates also varied by GBCA subtype (overall
p
< 0.001). There was significant interaction between GBCA and pharmacological stressor (interaction
p
= 0.025), with AAE rates ranging between 0 and 10% for certain GBCA/stressor combinations. There was further marginal evidence that higher GBCA volume was associated with higher AAE incidence (OR = 1.02,
p
= 0.05).
Conclusion
GBCA-enhanced CMR imaging demonstrates low AAE rates comparable to those of other body regions. AAE likelihood correlates with GBCA subtype, pharmacological stressor, and imaging indication. Intravenous fluid administration in patients with cardiac impairment might contribute to these findings.
Key Points
• Acute adverse event rates in cardiac magnetic resonance (CMR) imaging with gadolinium-based contrast agents (GBCAs) are low (0.36%), especially for severe adverse events (0.033%).
• Mild and moderate adverse events are more frequent during stress CMR imaging.
• Physiologic AAEs are more common than allergic AAEs in CMR imaging.</abstract><cop>Berlin/Heidelberg</cop><pub>Springer Berlin Heidelberg</pub><pmid>31041566</pmid><doi>10.1007/s00330-019-06171-2</doi><tpages>10</tpages><orcidid>https://orcid.org/0000-0003-4879-0438</orcidid><orcidid>https://orcid.org/0000-0003-0297-7942</orcidid><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0938-7994 |
| ispartof | European radiology, 2019-07, Vol.29 (7), p.3686-3695 |
| issn | 0938-7994 1432-1084 |
| language | eng |
| recordid | cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6554260 |
| source | MEDLINE; SpringerLink Journals - AutoHoldings |
| subjects | Acute Disease Administration, Intravenous Cardiac Cardiovascular disease Cardiovascular Diseases - diagnosis Contrast agents Contrast media Coronary artery Coronary artery disease Diagnostic Radiology Drug-Related Side Effects and Adverse Reactions - epidemiology Drug-Related Side Effects and Adverse Reactions - etiology Europe - epidemiology Female Gadolinium Heart diseases Humans Imaging Incidence Internal Medicine Interventional Radiology Intravenous administration Life Sciences Magnetic resonance imaging Magnetic Resonance Imaging, Cine - adverse effects Magnetic Resonance Imaging, Cine - methods Male Medical imaging Medicine Medicine & Public Health Middle Aged Myocarditis Neuroradiology Organometallic Compounds - administration & dosage Organometallic Compounds - adverse effects Pharmacology Population studies Radiology Registries Resonance Retrospective Studies Societies, Medical Ultrasound |
| title | Acute adverse events in cardiac MR imaging with gadolinium-based contrast agents: results from the European Society of Cardiovascular Radiology (ESCR) MRCT Registry in 72,839 patients |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-21T11%3A05%3A25IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Acute%20adverse%20events%20in%20cardiac%20MR%20imaging%20with%20gadolinium-based%20contrast%20agents:%20results%20from%20the%20European%20Society%20of%20Cardiovascular%20Radiology%20(ESCR)%20MRCT%20Registry%20in%2072,839%20patients&rft.jtitle=European%20radiology&rft.au=Uhlig,%20Johannes&rft.aucorp=Daniel%20Thomas&rft.date=2019-07-01&rft.volume=29&rft.issue=7&rft.spage=3686&rft.epage=3695&rft.pages=3686-3695&rft.issn=0938-7994&rft.eissn=1432-1084&rft_id=info:doi/10.1007/s00330-019-06171-2&rft_dat=%3Cproquest_pubme%3E2217185175%3C/proquest_pubme%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2217185175&rft_id=info:pmid/31041566&rfr_iscdi=true |