Comprehensive Analysis of lncRNA–miRNA– mRNA Network Ascertains Prognostic Factors in Patients with Colon Cancer

Background: Non-coding RNAs are competing endogenous RNAs in the occurrence and development of tumorigenesis; numerous microRNAs are aberrantly expressed in colon cancer tissues and play significant roles in oncogenesis development and metastasis. However, large clinical and RNA data are lacking to...

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Veröffentlicht in:	Technology in cancer research & treatment 2019-01, Vol.18, p.1533033819853237-1533033819853237
Hauptverfasser:	Gao, Zhenzhen, Fu, Peng, Yu, Zhengyi, Zhen, Fuxi, Gu, Yanhong
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Cell adhesion & migration Cell migration Colon cancer Colonic Neoplasms - diagnosis Colonic Neoplasms - genetics Colonic Neoplasms - mortality Colorectal cancer Computational Biology Encyclopedias Gene Expression Regulation, Neoplastic Gene Ontology Gene regulation Gene Regulatory Networks Genes Genomes Humans Hypoxia Kaplan-Meier Estimate Medical prognosis Metastases MicroRNAs MicroRNAs - genetics Middle Aged miRNA Neoplasm Metastasis Neoplasm Staging Non-coding RNA Ontology Original Prognosis RNA Interference RNA, Long Noncoding - genetics RNA, Messenger - genetics Survival analysis Transcription Transforming growth factor-b Tumorigenesis
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