Hepatocyte Nuclear Factor 4 alpha (HNF4α) Activation is Essential for Termination of Liver Regeneration

Hepatocyte Nuclear Factor 4 alpha (HNF4α) is critical for hepatic differentiation. Recent studies have highlighted its role in inhibition of hepatocyte proliferation and tumor suppression. However, the role of HNF4α in liver regeneration is not known. We hypothesized that hepatocytes modulate HNF4α...

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Veröffentlicht in:Hepatology (Baltimore, Md.) Md.), 2019-03, Vol.70 (2), p.666-681
Hauptverfasser: Huck, Ian, Gunewardena, Sumedha, Espanol-Suner, Regina, Willenbring, Holger, Apte, Udayan
Format: Artikel
Sprache:eng
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