Effects of a Home‐based Exercise Program on Anxiety and Mood Disturbances in Older Adults with Cancer Receiving Chemotherapy
BACKGROUND/OBJECTIVE Exercise interventions improve anxiety and mood disturbances in patients with cancer. However, studies are limited in older adults with cancer. We assessed the effects of exercise on anxiety, mood, and social and emotional well‐being in older patients with cancer during their fi...
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| Veröffentlicht in: | Journal of the American Geriatrics Society (JAGS) 2019-05, Vol.67 (5), p.1005-1011 |
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| creator | Loh, Kah Poh Kleckner, Ian R. Lin, Po‐Ju Mohile, Supriya G. Canin, Beverly E. Flannery, Marie A. Fung, Chunkit Dunne, Richard F. Bautista, Javier Culakova, Eva Kleckner, Amber S. Peppone, Luke J. Janelsins, Michelle McHugh, Colin Conlin, Alison Cho, Jonathan K. Kasbari, Sameer Esparaz, Benjamin T. Kuebler, J. Philip Mustian, Karen M. |
| description | BACKGROUND/OBJECTIVE
Exercise interventions improve anxiety and mood disturbances in patients with cancer. However, studies are limited in older adults with cancer. We assessed the effects of exercise on anxiety, mood, and social and emotional well‐being in older patients with cancer during their first 6 weeks of chemotherapy.
DESIGN
Exploratory secondary analysis of a randomized controlled trial (RCT).
SETTING
Community oncology practices.
PARTICIPANTS
Older patients (aged 60 years or older) undergoing chemotherapy (N = 252).
INTERVENTION
Patients were randomized to Exercise for Cancer Patients (EXCAP) or usual care (control) for the first 6 weeks of chemotherapy. EXCAP is a home‐based, low‐ to moderate‐intensity progressive walking and resistance training program.
MEASUREMENTS
Analysis of covariance, with study arm as the factor, baseline value as the covariate, and study arm × baseline interaction, was used to evaluate arm effects on postintervention anxiety (State Trait Anxiety Inventory [STAI]), mood (Profile of Mood States [POMS]), and social and emotional well‐being (Functional Assessment of Cancer Therapy–General subscales) after 6 weeks.
RESULTS
Median age was 67 years; 77% had breast cancer. Statistically significant group differences were observed in the STAI score (P = .001), POMS score (P = .022), social well‐being (P = .002), and emotional well‐being (P = .048). For each outcome, EXCAP patients with worse baseline scores had larger improvements at 6 weeks; these improvements were clinically significant for STAI score and social well‐being.
CONCLUSIONS
Among older cancer patients receiving chemotherapy, a 6‐week structured exercise program improved anxiety and mood, especially among those participants with worse baseline symptoms. Additional RCTs are needed to confirm these findings and evaluate the appropriate exercise prescription for managing anxiety, mood, and well‐being in this patient population. J Am Geriatr Soc 67:1005–1011, 2019. |
| doi_str_mv | 10.1111/jgs.15951 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6544022</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2217481554</sourcerecordid><originalsourceid>FETCH-LOGICAL-c4431-171cdcdd545ef7a7e60f77bd4fd5588a0adeedaae797e3e1957a3a76773879e53</originalsourceid><addsrcrecordid>eNp1kc9u1DAQhy0EokvhwAsgS1zgkNaT2HFyQVot2xZUVMSfs-W1J7teJfbWTtrupeIReEaehCxbKkBiLnOYT59-ox8hz4EdwTjH62U6AlELeEAmIIo8ExzEQzJhjOVZVQI_IE9SWjMGOauqx-SgAFZwUcOE3M6bBk2faGiopmehwx_fvi90QkvnNxiNS0g_xrCMuqPB06m_cdhvqfaWfgjB0rcu9UNcaG8wUefpRWsx0qkd2tF57foVne1ukX5Cg-7K-SWdrbAL_Qqj3myfkkeNbhM-u9uH5OvJ_MvsLDu_OH03m55nhvMCMpBgrLFWcIGN1BJL1ki5sLyxQlSVZtoiWq1R1hILhFpIXWhZSllUskZRHJI3e-9mWHRoDfo-6lZtout03Kqgnfr74t1KLcOVKgXnLM9Hwas7QQyXA6ZedS4ZbFvtMQxJ5TlIXoEQfERf_oOuwxD9-N6OKosSWLUTvt5TJoaUIjb3YYCpXatqbFX9anVkX_yZ_p78XeMIHO-Ba9fi9v8m9f708175E2Eurqk</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2216361082</pqid></control><display><type>article</type><title>Effects of a Home‐based Exercise Program on Anxiety and Mood Disturbances in Older Adults with Cancer Receiving Chemotherapy</title><source>MEDLINE</source><source>Wiley Online Library Journals Frontfile Complete</source><creator>Loh, Kah Poh ; Kleckner, Ian R. ; Lin, Po‐Ju ; Mohile, Supriya G. ; Canin, Beverly E. ; Flannery, Marie A. ; Fung, Chunkit ; Dunne, Richard F. ; Bautista, Javier ; Culakova, Eva ; Kleckner, Amber S. ; Peppone, Luke J. ; Janelsins, Michelle ; McHugh, Colin ; Conlin, Alison ; Cho, Jonathan K. ; Kasbari, Sameer ; Esparaz, Benjamin T. ; Kuebler, J. Philip ; Mustian, Karen M.</creator><creatorcontrib>Loh, Kah Poh ; Kleckner, Ian R. ; Lin, Po‐Ju ; Mohile, Supriya G. ; Canin, Beverly E. ; Flannery, Marie A. ; Fung, Chunkit ; Dunne, Richard F. ; Bautista, Javier ; Culakova, Eva ; Kleckner, Amber S. ; Peppone, Luke J. ; Janelsins, Michelle ; McHugh, Colin ; Conlin, Alison ; Cho, Jonathan K. ; Kasbari, Sameer ; Esparaz, Benjamin T. ; Kuebler, J. Philip ; Mustian, Karen M.</creatorcontrib><description>BACKGROUND/OBJECTIVE
Exercise interventions improve anxiety and mood disturbances in patients with cancer. However, studies are limited in older adults with cancer. We assessed the effects of exercise on anxiety, mood, and social and emotional well‐being in older patients with cancer during their first 6 weeks of chemotherapy.
DESIGN
Exploratory secondary analysis of a randomized controlled trial (RCT).
SETTING
Community oncology practices.
PARTICIPANTS
Older patients (aged 60 years or older) undergoing chemotherapy (N = 252).
INTERVENTION
Patients were randomized to Exercise for Cancer Patients (EXCAP) or usual care (control) for the first 6 weeks of chemotherapy. EXCAP is a home‐based, low‐ to moderate‐intensity progressive walking and resistance training program.
MEASUREMENTS
Analysis of covariance, with study arm as the factor, baseline value as the covariate, and study arm × baseline interaction, was used to evaluate arm effects on postintervention anxiety (State Trait Anxiety Inventory [STAI]), mood (Profile of Mood States [POMS]), and social and emotional well‐being (Functional Assessment of Cancer Therapy–General subscales) after 6 weeks.
RESULTS
Median age was 67 years; 77% had breast cancer. Statistically significant group differences were observed in the STAI score (P = .001), POMS score (P = .022), social well‐being (P = .002), and emotional well‐being (P = .048). For each outcome, EXCAP patients with worse baseline scores had larger improvements at 6 weeks; these improvements were clinically significant for STAI score and social well‐being.
CONCLUSIONS
Among older cancer patients receiving chemotherapy, a 6‐week structured exercise program improved anxiety and mood, especially among those participants with worse baseline symptoms. Additional RCTs are needed to confirm these findings and evaluate the appropriate exercise prescription for managing anxiety, mood, and well‐being in this patient population. J Am Geriatr Soc 67:1005–1011, 2019.</description><identifier>ISSN: 0002-8614</identifier><identifier>EISSN: 1532-5415</identifier><identifier>DOI: 10.1111/jgs.15951</identifier><identifier>PMID: 31034591</identifier><language>eng</language><publisher>Hoboken, USA: John Wiley & Sons, Inc</publisher><subject>Aged ; Aged, 80 and over ; Antineoplastic Agents - therapeutic use ; Anxiety ; Anxiety - etiology ; Anxiety - psychology ; Anxiety - rehabilitation ; Breast cancer ; Cancer ; Chemotherapy ; Clinical significance ; Emotions ; exercise ; Exercise - psychology ; Female ; Follow-Up Studies ; Humans ; Male ; Mental Health ; Middle Aged ; Mood ; Mood Disorders - etiology ; Mood Disorders - psychology ; Mood Disorders - rehabilitation ; Neoplasms - complications ; Neoplasms - drug therapy ; Neoplasms - psychology ; older adults with cancer ; Older people ; Oncology ; Physical training ; Prognosis ; Quality of Life ; Resistance Training - methods ; Retrospective Studies ; social and emotional well‐being ; Statistical analysis ; Walking ; Well being</subject><ispartof>Journal of the American Geriatrics Society (JAGS), 2019-05, Vol.67 (5), p.1005-1011</ispartof><rights>2019 The American Geriatrics Society</rights><rights>2019 The American Geriatrics Society.</rights><rights>2019 American Geriatrics Society and Wiley Periodicals, Inc.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c4431-171cdcdd545ef7a7e60f77bd4fd5588a0adeedaae797e3e1957a3a76773879e53</citedby><cites>FETCH-LOGICAL-c4431-171cdcdd545ef7a7e60f77bd4fd5588a0adeedaae797e3e1957a3a76773879e53</cites><orcidid>0000-0002-6978-0418</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1111%2Fjgs.15951$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1111%2Fjgs.15951$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>230,314,776,780,881,1411,27901,27902,45550,45551</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/31034591$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Loh, Kah Poh</creatorcontrib><creatorcontrib>Kleckner, Ian R.</creatorcontrib><creatorcontrib>Lin, Po‐Ju</creatorcontrib><creatorcontrib>Mohile, Supriya G.</creatorcontrib><creatorcontrib>Canin, Beverly E.</creatorcontrib><creatorcontrib>Flannery, Marie A.</creatorcontrib><creatorcontrib>Fung, Chunkit</creatorcontrib><creatorcontrib>Dunne, Richard F.</creatorcontrib><creatorcontrib>Bautista, Javier</creatorcontrib><creatorcontrib>Culakova, Eva</creatorcontrib><creatorcontrib>Kleckner, Amber S.</creatorcontrib><creatorcontrib>Peppone, Luke J.</creatorcontrib><creatorcontrib>Janelsins, Michelle</creatorcontrib><creatorcontrib>McHugh, Colin</creatorcontrib><creatorcontrib>Conlin, Alison</creatorcontrib><creatorcontrib>Cho, Jonathan K.</creatorcontrib><creatorcontrib>Kasbari, Sameer</creatorcontrib><creatorcontrib>Esparaz, Benjamin T.</creatorcontrib><creatorcontrib>Kuebler, J. Philip</creatorcontrib><creatorcontrib>Mustian, Karen M.</creatorcontrib><title>Effects of a Home‐based Exercise Program on Anxiety and Mood Disturbances in Older Adults with Cancer Receiving Chemotherapy</title><title>Journal of the American Geriatrics Society (JAGS)</title><addtitle>J Am Geriatr Soc</addtitle><description>BACKGROUND/OBJECTIVE
Exercise interventions improve anxiety and mood disturbances in patients with cancer. However, studies are limited in older adults with cancer. We assessed the effects of exercise on anxiety, mood, and social and emotional well‐being in older patients with cancer during their first 6 weeks of chemotherapy.
DESIGN
Exploratory secondary analysis of a randomized controlled trial (RCT).
SETTING
Community oncology practices.
PARTICIPANTS
Older patients (aged 60 years or older) undergoing chemotherapy (N = 252).
INTERVENTION
Patients were randomized to Exercise for Cancer Patients (EXCAP) or usual care (control) for the first 6 weeks of chemotherapy. EXCAP is a home‐based, low‐ to moderate‐intensity progressive walking and resistance training program.
MEASUREMENTS
Analysis of covariance, with study arm as the factor, baseline value as the covariate, and study arm × baseline interaction, was used to evaluate arm effects on postintervention anxiety (State Trait Anxiety Inventory [STAI]), mood (Profile of Mood States [POMS]), and social and emotional well‐being (Functional Assessment of Cancer Therapy–General subscales) after 6 weeks.
RESULTS
Median age was 67 years; 77% had breast cancer. Statistically significant group differences were observed in the STAI score (P = .001), POMS score (P = .022), social well‐being (P = .002), and emotional well‐being (P = .048). For each outcome, EXCAP patients with worse baseline scores had larger improvements at 6 weeks; these improvements were clinically significant for STAI score and social well‐being.
CONCLUSIONS
Among older cancer patients receiving chemotherapy, a 6‐week structured exercise program improved anxiety and mood, especially among those participants with worse baseline symptoms. Additional RCTs are needed to confirm these findings and evaluate the appropriate exercise prescription for managing anxiety, mood, and well‐being in this patient population. J Am Geriatr Soc 67:1005–1011, 2019.</description><subject>Aged</subject><subject>Aged, 80 and over</subject><subject>Antineoplastic Agents - therapeutic use</subject><subject>Anxiety</subject><subject>Anxiety - etiology</subject><subject>Anxiety - psychology</subject><subject>Anxiety - rehabilitation</subject><subject>Breast cancer</subject><subject>Cancer</subject><subject>Chemotherapy</subject><subject>Clinical significance</subject><subject>Emotions</subject><subject>exercise</subject><subject>Exercise - psychology</subject><subject>Female</subject><subject>Follow-Up Studies</subject><subject>Humans</subject><subject>Male</subject><subject>Mental Health</subject><subject>Middle Aged</subject><subject>Mood</subject><subject>Mood Disorders - etiology</subject><subject>Mood Disorders - psychology</subject><subject>Mood Disorders - rehabilitation</subject><subject>Neoplasms - complications</subject><subject>Neoplasms - drug therapy</subject><subject>Neoplasms - psychology</subject><subject>older adults with cancer</subject><subject>Older people</subject><subject>Oncology</subject><subject>Physical training</subject><subject>Prognosis</subject><subject>Quality of Life</subject><subject>Resistance Training - methods</subject><subject>Retrospective Studies</subject><subject>social and emotional well‐being</subject><subject>Statistical analysis</subject><subject>Walking</subject><subject>Well being</subject><issn>0002-8614</issn><issn>1532-5415</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2019</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp1kc9u1DAQhy0EokvhwAsgS1zgkNaT2HFyQVot2xZUVMSfs-W1J7teJfbWTtrupeIReEaehCxbKkBiLnOYT59-ox8hz4EdwTjH62U6AlELeEAmIIo8ExzEQzJhjOVZVQI_IE9SWjMGOauqx-SgAFZwUcOE3M6bBk2faGiopmehwx_fvi90QkvnNxiNS0g_xrCMuqPB06m_cdhvqfaWfgjB0rcu9UNcaG8wUefpRWsx0qkd2tF57foVne1ukX5Cg-7K-SWdrbAL_Qqj3myfkkeNbhM-u9uH5OvJ_MvsLDu_OH03m55nhvMCMpBgrLFWcIGN1BJL1ki5sLyxQlSVZtoiWq1R1hILhFpIXWhZSllUskZRHJI3e-9mWHRoDfo-6lZtout03Kqgnfr74t1KLcOVKgXnLM9Hwas7QQyXA6ZedS4ZbFvtMQxJ5TlIXoEQfERf_oOuwxD9-N6OKosSWLUTvt5TJoaUIjb3YYCpXatqbFX9anVkX_yZ_p78XeMIHO-Ba9fi9v8m9f708175E2Eurqk</recordid><startdate>201905</startdate><enddate>201905</enddate><creator>Loh, Kah Poh</creator><creator>Kleckner, Ian R.</creator><creator>Lin, Po‐Ju</creator><creator>Mohile, Supriya G.</creator><creator>Canin, Beverly E.</creator><creator>Flannery, Marie A.</creator><creator>Fung, Chunkit</creator><creator>Dunne, Richard F.</creator><creator>Bautista, Javier</creator><creator>Culakova, Eva</creator><creator>Kleckner, Amber S.</creator><creator>Peppone, Luke J.</creator><creator>Janelsins, Michelle</creator><creator>McHugh, Colin</creator><creator>Conlin, Alison</creator><creator>Cho, Jonathan K.</creator><creator>Kasbari, Sameer</creator><creator>Esparaz, Benjamin T.</creator><creator>Kuebler, J. Philip</creator><creator>Mustian, Karen M.</creator><general>John Wiley & Sons, Inc</general><general>Wiley Subscription Services, Inc</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7QP</scope><scope>7TK</scope><scope>K9.</scope><scope>NAPCQ</scope><scope>7X8</scope><scope>5PM</scope><orcidid>https://orcid.org/0000-0002-6978-0418</orcidid></search><sort><creationdate>201905</creationdate><title>Effects of a Home‐based Exercise Program on Anxiety and Mood Disturbances in Older Adults with Cancer Receiving Chemotherapy</title><author>Loh, Kah Poh ; Kleckner, Ian R. ; Lin, Po‐Ju ; Mohile, Supriya G. ; Canin, Beverly E. ; Flannery, Marie A. ; Fung, Chunkit ; Dunne, Richard F. ; Bautista, Javier ; Culakova, Eva ; Kleckner, Amber S. ; Peppone, Luke J. ; Janelsins, Michelle ; McHugh, Colin ; Conlin, Alison ; Cho, Jonathan K. ; Kasbari, Sameer ; Esparaz, Benjamin T. ; Kuebler, J. Philip ; Mustian, Karen M.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c4431-171cdcdd545ef7a7e60f77bd4fd5588a0adeedaae797e3e1957a3a76773879e53</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2019</creationdate><topic>Aged</topic><topic>Aged, 80 and over</topic><topic>Antineoplastic Agents - therapeutic use</topic><topic>Anxiety</topic><topic>Anxiety - etiology</topic><topic>Anxiety - psychology</topic><topic>Anxiety - rehabilitation</topic><topic>Breast cancer</topic><topic>Cancer</topic><topic>Chemotherapy</topic><topic>Clinical significance</topic><topic>Emotions</topic><topic>exercise</topic><topic>Exercise - psychology</topic><topic>Female</topic><topic>Follow-Up Studies</topic><topic>Humans</topic><topic>Male</topic><topic>Mental Health</topic><topic>Middle Aged</topic><topic>Mood</topic><topic>Mood Disorders - etiology</topic><topic>Mood Disorders - psychology</topic><topic>Mood Disorders - rehabilitation</topic><topic>Neoplasms - complications</topic><topic>Neoplasms - drug therapy</topic><topic>Neoplasms - psychology</topic><topic>older adults with cancer</topic><topic>Older people</topic><topic>Oncology</topic><topic>Physical training</topic><topic>Prognosis</topic><topic>Quality of Life</topic><topic>Resistance Training - methods</topic><topic>Retrospective Studies</topic><topic>social and emotional well‐being</topic><topic>Statistical analysis</topic><topic>Walking</topic><topic>Well being</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Loh, Kah Poh</creatorcontrib><creatorcontrib>Kleckner, Ian R.</creatorcontrib><creatorcontrib>Lin, Po‐Ju</creatorcontrib><creatorcontrib>Mohile, Supriya G.</creatorcontrib><creatorcontrib>Canin, Beverly E.</creatorcontrib><creatorcontrib>Flannery, Marie A.</creatorcontrib><creatorcontrib>Fung, Chunkit</creatorcontrib><creatorcontrib>Dunne, Richard F.</creatorcontrib><creatorcontrib>Bautista, Javier</creatorcontrib><creatorcontrib>Culakova, Eva</creatorcontrib><creatorcontrib>Kleckner, Amber S.</creatorcontrib><creatorcontrib>Peppone, Luke J.</creatorcontrib><creatorcontrib>Janelsins, Michelle</creatorcontrib><creatorcontrib>McHugh, Colin</creatorcontrib><creatorcontrib>Conlin, Alison</creatorcontrib><creatorcontrib>Cho, Jonathan K.</creatorcontrib><creatorcontrib>Kasbari, Sameer</creatorcontrib><creatorcontrib>Esparaz, Benjamin T.</creatorcontrib><creatorcontrib>Kuebler, J. Philip</creatorcontrib><creatorcontrib>Mustian, Karen M.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Calcium & Calcified Tissue Abstracts</collection><collection>Neurosciences Abstracts</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Premium</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Journal of the American Geriatrics Society (JAGS)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Loh, Kah Poh</au><au>Kleckner, Ian R.</au><au>Lin, Po‐Ju</au><au>Mohile, Supriya G.</au><au>Canin, Beverly E.</au><au>Flannery, Marie A.</au><au>Fung, Chunkit</au><au>Dunne, Richard F.</au><au>Bautista, Javier</au><au>Culakova, Eva</au><au>Kleckner, Amber S.</au><au>Peppone, Luke J.</au><au>Janelsins, Michelle</au><au>McHugh, Colin</au><au>Conlin, Alison</au><au>Cho, Jonathan K.</au><au>Kasbari, Sameer</au><au>Esparaz, Benjamin T.</au><au>Kuebler, J. Philip</au><au>Mustian, Karen M.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Effects of a Home‐based Exercise Program on Anxiety and Mood Disturbances in Older Adults with Cancer Receiving Chemotherapy</atitle><jtitle>Journal of the American Geriatrics Society (JAGS)</jtitle><addtitle>J Am Geriatr Soc</addtitle><date>2019-05</date><risdate>2019</risdate><volume>67</volume><issue>5</issue><spage>1005</spage><epage>1011</epage><pages>1005-1011</pages><issn>0002-8614</issn><eissn>1532-5415</eissn><abstract>BACKGROUND/OBJECTIVE
Exercise interventions improve anxiety and mood disturbances in patients with cancer. However, studies are limited in older adults with cancer. We assessed the effects of exercise on anxiety, mood, and social and emotional well‐being in older patients with cancer during their first 6 weeks of chemotherapy.
DESIGN
Exploratory secondary analysis of a randomized controlled trial (RCT).
SETTING
Community oncology practices.
PARTICIPANTS
Older patients (aged 60 years or older) undergoing chemotherapy (N = 252).
INTERVENTION
Patients were randomized to Exercise for Cancer Patients (EXCAP) or usual care (control) for the first 6 weeks of chemotherapy. EXCAP is a home‐based, low‐ to moderate‐intensity progressive walking and resistance training program.
MEASUREMENTS
Analysis of covariance, with study arm as the factor, baseline value as the covariate, and study arm × baseline interaction, was used to evaluate arm effects on postintervention anxiety (State Trait Anxiety Inventory [STAI]), mood (Profile of Mood States [POMS]), and social and emotional well‐being (Functional Assessment of Cancer Therapy–General subscales) after 6 weeks.
RESULTS
Median age was 67 years; 77% had breast cancer. Statistically significant group differences were observed in the STAI score (P = .001), POMS score (P = .022), social well‐being (P = .002), and emotional well‐being (P = .048). For each outcome, EXCAP patients with worse baseline scores had larger improvements at 6 weeks; these improvements were clinically significant for STAI score and social well‐being.
CONCLUSIONS
Among older cancer patients receiving chemotherapy, a 6‐week structured exercise program improved anxiety and mood, especially among those participants with worse baseline symptoms. Additional RCTs are needed to confirm these findings and evaluate the appropriate exercise prescription for managing anxiety, mood, and well‐being in this patient population. J Am Geriatr Soc 67:1005–1011, 2019.</abstract><cop>Hoboken, USA</cop><pub>John Wiley & Sons, Inc</pub><pmid>31034591</pmid><doi>10.1111/jgs.15951</doi><tpages>7</tpages><orcidid>https://orcid.org/0000-0002-6978-0418</orcidid><oa>free_for_read</oa></addata></record> |
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| ispartof | Journal of the American Geriatrics Society (JAGS), 2019-05, Vol.67 (5), p.1005-1011 |
| issn | 0002-8614 1532-5415 |
| language | eng |
| recordid | cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6544022 |
| source | MEDLINE; Wiley Online Library Journals Frontfile Complete |
| subjects | Aged Aged, 80 and over Antineoplastic Agents - therapeutic use Anxiety Anxiety - etiology Anxiety - psychology Anxiety - rehabilitation Breast cancer Cancer Chemotherapy Clinical significance Emotions exercise Exercise - psychology Female Follow-Up Studies Humans Male Mental Health Middle Aged Mood Mood Disorders - etiology Mood Disorders - psychology Mood Disorders - rehabilitation Neoplasms - complications Neoplasms - drug therapy Neoplasms - psychology older adults with cancer Older people Oncology Physical training Prognosis Quality of Life Resistance Training - methods Retrospective Studies social and emotional well‐being Statistical analysis Walking Well being |
| title | Effects of a Home‐based Exercise Program on Anxiety and Mood Disturbances in Older Adults with Cancer Receiving Chemotherapy |
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