Erythropoietin inhibits SGK1-dependent Th17 cell induction and Th17 cell–dependent kidney disease

IL-17–producing CD4 + (Th17) cells are pathogenically linked to autoimmunity and, specifically, to autoimmune kidney disease. The newly recognized immunoregulatory functions of erythropoietin (EPO) and its predominant intrarenal source suggested that EPO physiologically regulates Th17 cell different...

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Veröffentlicht in:	JCI insight 2019-05, Vol.4 (10)
Hauptverfasser:	Donadei, Chiara, Angeletti, Andrea, Cantarelli, Chiara, D’Agati, Vivette D., La Manna, Gaetano, Fiaccadori, Enrico, Horwitz, Julian K., Xiong, Huabao, Guglielmo, Chiara, Hartzell, Susan, Madsen, Joren C., Maggiore, Umberto, Heeger, Peter S., Cravedi, Paolo
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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