MERIT: Systematic Analysis and Characterization of Mutational Effect on RNA Interactome Topology

The interaction between RNA‐binding proteins (RBPs) and RNA plays an important role in regulating cellular function. However, decoding genome‐wide protein–RNA regulatory networks as well as how cancer‐related mutations impair RNA regulatory activities in hepatocellular carcinoma (HCC) remains mostly...

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Veröffentlicht in:	Hepatology (Baltimore, Md.) Md.), 2019-08, Vol.70 (2), p.532-546
Hauptverfasser:	Li, Yongsheng, McGrail, Daniel J., Xu, Juan, Li, Junyi, Liu, Ning‐Ning, Sun, Ming, Lin, Richard, Pancsa, Rita, Zhang, Jiwei, Lee, Ju‐Seog, Wang, Hui, Mills, Gordon B., Li, Xia, Yi, Song, Sahni, Nidhi
Format:	Artikel
Sprache:	eng
Schlagworte:	Cancer Carcinoma, Hepatocellular - genetics Carcinoma, Hepatocellular - mortality Carcinoma, Hepatocellular - pathology Cell Proliferation Computer applications Gene Regulatory Networks Genes Genomes Genotypes Hepatocellular carcinoma Hepatology Humans Liver cancer Liver Neoplasms - genetics Liver Neoplasms - mortality Liver Neoplasms - pathology Mutation Original Phenotypes Precision medicine Protein Interaction Maps Proteins Reproductive fitness Ribonucleic acid RNA RNA - genetics RNA-Binding Proteins - genetics Survival Rate
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