A multicentre longitudinal study of flortaucipir (18F) in normal ageing, mild cognitive impairment and Alzheimer's disease dementia

The advent of tau-targeted PET tracers such as flortaucipir (18F) (flortaucipir, also known as 18F-AV-1451 or 18F-T807) have made it possible to investigate the sequence of development of tau in relationship to age, amyloid-β, and to the development of cognitive impairment due to Alzheimer's di...

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Veröffentlicht in:	Brain (London, England : 1878) England : 1878), 2019-06, Vol.142 (6), p.1723-1735
Hauptverfasser:	Pontecorvo, Michael J, Devous, Michael D, Kennedy, Ian, Navitsky, Michael, Lu, Ming, Galante, Nicholas, Salloway, Stephen, Doraiswamy, P Murali, Southekal, Sudeepti, Arora, Anupa K, McGeehan, Anne, Lim, Nathaniel C, Xiong, Hui, Truocchio, Stephen P, Joshi, Abhinay D, Shcherbinin, Sergey, Teske, Brian, Fleisher, Adam S, Mintun, Mark A
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Aging Alzheimer Disease - pathology Amyloid - metabolism Amyloid beta-Peptides - metabolism Brain - metabolism Brain - pathology Carbolines Cognition - physiology Cognition Disorders - pathology Cognitive Dysfunction - pathology Dementia - pathology Editor's Choice Female Humans Longitudinal Studies Male Middle Aged Original tau Proteins - metabolism
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