Differential effects of alkyl gallates on quorum sensing in Pseudomonas aeruginosa

Virulence factors and biofilms constitute attractive targets for the prevention of infections caused by multidrug-resistant bacteria. Among alkyl gallates, propyl gallate (PG) and octyl gallate (OG) are used as food preservatives. Here we found that alkyl gallates differentially affect virulence, bi...

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Veröffentlicht in:	Scientific reports 2019-05, Vol.9 (1), p.7741-7741, Article 7741
Hauptverfasser:	Kim, Bomin, ParK, Ji-Su, Choi, Ha-Young, Kwak, Jin-Hwan, Kim, Won-Gon
Format:	Artikel
Sprache:	eng
Schlagworte:	101/58 14/19 14/34 631/326/22/1290 631/326/46 64/11 64/60 Animals Anti-Bacterial Agents - pharmacology Bacterial Proteins - metabolism Biofilms Biofilms - drug effects Caenorhabditis elegans - metabolism Caenorhabditis elegans - microbiology Cell viability Drug Resistance, Multiple, Bacterial - drug effects Elastase Female Gallic Acid - analogs & derivatives Gallic Acid - pharmacology Gene expression Glycolipids - metabolism Humanities and Social Sciences Mice Mice, Inbred BALB C - microbiology multidisciplinary Multidrug resistance Pancreatic Elastase - metabolism Preservatives Propyl Gallate Pseudomonas aeruginosa Pseudomonas aeruginosa - drug effects Pseudomonas aeruginosa - metabolism Pyocyanin Pyocyanine - metabolism Quorum sensing Quorum Sensing - drug effects Quorum Sensing - physiology RhlR protein Science Science (multidisciplinary) Virulence - drug effects Virulence factors Virulence Factors - genetics
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