The Synthetic Phenotype of Δ bamB Δ bamE Double Mutants Results from a Lethal Jamming of the Bam Complex by the Lipoprotein RcsF

The selective permeability of the Gram-negative outer membrane (OM) is maintained by integral β-barrel outer membrane proteins (OMPs). The heteropentomeric β-barrel assembly machine (Bam) folds and inserts OMPs into the OM. Coordination of the essential proteins BamA and BamD is critical for OMP ass...

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Veröffentlicht in:	mBio 2019-05, Vol.10 (3)
Hauptverfasser:	Hart, Elizabeth M, Gupta, Meera, Wühr, Martin, Silhavy, Thomas J
Format:	Artikel
Sprache:	eng
Schlagworte:	Bacterial Outer Membrane Proteins - genetics Bacterial Outer Membrane Proteins - metabolism Escherichia coli - metabolism Escherichia coli Proteins - genetics Escherichia coli Proteins - metabolism Gene Deletion Lipoproteins - metabolism Microbial Viability Molecular Biology and Physiology Protein Multimerization
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