LincRNA‐p21 suppresses development of human prostate cancer through inhibition of PKM2

Objectives Previously, we found that long intergenic non‐coding RNA‐p21 (lincRNA‐p21) inhibited the development of human prostate cancer. However, the underlying molecular mechanisms are poorly understood. Here, we attempted to investigate the downstream targets of lincRNA‐p21 in prostate cancer. Ma...

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Veröffentlicht in:	Cell proliferation 2017-12, Vol.50 (6), p.n/a
Hauptverfasser:	Wang, Xiaohai, Xu, Yongzhi, Wang, Xingjie, Jiang, Chenyi, Han, Sha, Dong, Kai, Shen, Mengjun, Xu, Dongliang
Format:	Artikel
Sprache:	eng
Schlagworte:	Androgens Cancer Carrier Proteins - metabolism Cell growth Cell Line, Tumor Cell proliferation Cell Proliferation - drug effects Cyclin-dependent kinase inhibitor p21 Down-Regulation Glycolysis Glycolysis - physiology Humans Male Membrane Proteins - metabolism Molecular modelling Non-coding RNA Original Patients Prostate cancer Prostatic Neoplasms - genetics Pyruvates - pharmacology Rapamycin Ribonucleic acid RNA RNA, Long Noncoding - genetics Thyroid Hormone-Binding Proteins Thyroid Hormones - metabolism TOR protein Tumorigenesis Tumors Xenografts
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