Higher ultrafiltration rate is associated with right ventricular mechanical dispersion
Ultrafiltration rate is one of the major determinants of adverse outcomes in patients undergoing hemodialysis (HD) therapy. Previous studies have focused on the impact of HD on right ventricular (RV) peak strain values. However, the influence of HD on the temporal characteristics of deformation has...
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| Veröffentlicht in: | Anatolian journal of cardiology 2019-04, Vol.21 (4), p.206-213 |
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| creator | Ünlü, Serkan Pagourelias, Efstathios Sezenöz, Burak Şahinarslan, Asife Uludağ, Orhan Mecit Gökalp, Gökhan Arınsoy, Turgay Çengel, Atiye |
| description | Ultrafiltration rate is one of the major determinants of adverse outcomes in patients undergoing hemodialysis (HD) therapy. Previous studies have focused on the impact of HD on right ventricular (RV) peak strain values. However, the influence of HD on the temporal characteristics of deformation has not been reported yet. The aim of the present study was to evaluate the impact of high ultrafiltration rate (HUR) on RV mechanical dyssynchrony.
Echocardiographic images focused on the RV and left ventricle (LV) were obtained from 60 patients (49.2+-17.3 years, 22 female) before and after HD. Patients were divided into two groups according to ultrafiltration rate. Changes in echocardiographic parameters with HD were examined. Two-dimensional speckle-tracking strain analysis was used to assess deformation. Mechanical dispersion was measured as the standard deviation of time to peak longitudinal strain of six segments for RV and 18 segments for LV.
The average ultrafiltrated volume and ultrafiltration rate were 3000.1+-1007.9 mL and 11.4+-2.9 mL/kg/h, respectively. Global longitudinal strain (GLS) of the RV and LV decreased after HD in both groups. A significant difference was observed in RV mechanical dispersion with HD for patients in the high ultrafiltration group. A mild statistically insignificant increase in LV mechanical dispersion was also observed after HD.
HUR has a substantial impact on LV and RV GLS and RV dyssynchrony. Ultrafiltration rates and volumes should be kept as low as possible to achieve hemodynamic stability and tolerability. |
| doi_str_mv | 10.14744/AnatolJCardiol.2019.26243 |
| format | Article |
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Echocardiographic images focused on the RV and left ventricle (LV) were obtained from 60 patients (49.2+-17.3 years, 22 female) before and after HD. Patients were divided into two groups according to ultrafiltration rate. Changes in echocardiographic parameters with HD were examined. Two-dimensional speckle-tracking strain analysis was used to assess deformation. Mechanical dispersion was measured as the standard deviation of time to peak longitudinal strain of six segments for RV and 18 segments for LV.
The average ultrafiltrated volume and ultrafiltration rate were 3000.1+-1007.9 mL and 11.4+-2.9 mL/kg/h, respectively. Global longitudinal strain (GLS) of the RV and LV decreased after HD in both groups. A significant difference was observed in RV mechanical dispersion with HD for patients in the high ultrafiltration group. A mild statistically insignificant increase in LV mechanical dispersion was also observed after HD.
HUR has a substantial impact on LV and RV GLS and RV dyssynchrony. Ultrafiltration rates and volumes should be kept as low as possible to achieve hemodynamic stability and tolerability.</description><identifier>ISSN: 2149-2263</identifier><identifier>EISSN: 2149-2271</identifier><identifier>DOI: 10.14744/AnatolJCardiol.2019.26243</identifier><identifier>PMID: 30930445</identifier><language>eng</language><publisher>Turkey: Kare Publishing</publisher><subject>Cardiology ; Cardiovascular disease ; Clinical trials ; Heart failure ; Hemodialysis ; Ischemia ; Mortality ; Original Investigation ; Patients ; Studies ; Thoracic surgery ; Ultrasonic imaging</subject><ispartof>Anatolian journal of cardiology, 2019-04, Vol.21 (4), p.206-213</ispartof><rights>2019. Notwithstanding the ProQuest Terms and conditions, you may use this content in accordance with the associated terms available at http://www.anakarder.com/Copyright</rights><rights>Copyright: © 2019 Turkish Society of Cardiology 2019</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC6528502/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC6528502/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,727,780,784,864,885,27924,27925,53791,53793</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/30930445$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Ünlü, Serkan</creatorcontrib><creatorcontrib>Pagourelias, Efstathios</creatorcontrib><creatorcontrib>Sezenöz, Burak</creatorcontrib><creatorcontrib>Şahinarslan, Asife</creatorcontrib><creatorcontrib>Uludağ, Orhan Mecit</creatorcontrib><creatorcontrib>Gökalp, Gökhan</creatorcontrib><creatorcontrib>Arınsoy, Turgay</creatorcontrib><creatorcontrib>Çengel, Atiye</creatorcontrib><title>Higher ultrafiltration rate is associated with right ventricular mechanical dispersion</title><title>Anatolian journal of cardiology</title><addtitle>Anatol J Cardiol</addtitle><description>Ultrafiltration rate is one of the major determinants of adverse outcomes in patients undergoing hemodialysis (HD) therapy. Previous studies have focused on the impact of HD on right ventricular (RV) peak strain values. However, the influence of HD on the temporal characteristics of deformation has not been reported yet. The aim of the present study was to evaluate the impact of high ultrafiltration rate (HUR) on RV mechanical dyssynchrony.
Echocardiographic images focused on the RV and left ventricle (LV) were obtained from 60 patients (49.2+-17.3 years, 22 female) before and after HD. Patients were divided into two groups according to ultrafiltration rate. Changes in echocardiographic parameters with HD were examined. Two-dimensional speckle-tracking strain analysis was used to assess deformation. Mechanical dispersion was measured as the standard deviation of time to peak longitudinal strain of six segments for RV and 18 segments for LV.
The average ultrafiltrated volume and ultrafiltration rate were 3000.1+-1007.9 mL and 11.4+-2.9 mL/kg/h, respectively. Global longitudinal strain (GLS) of the RV and LV decreased after HD in both groups. A significant difference was observed in RV mechanical dispersion with HD for patients in the high ultrafiltration group. A mild statistically insignificant increase in LV mechanical dispersion was also observed after HD.
HUR has a substantial impact on LV and RV GLS and RV dyssynchrony. Ultrafiltration rates and volumes should be kept as low as possible to achieve hemodynamic stability and tolerability.</description><subject>Cardiology</subject><subject>Cardiovascular disease</subject><subject>Clinical trials</subject><subject>Heart failure</subject><subject>Hemodialysis</subject><subject>Ischemia</subject><subject>Mortality</subject><subject>Original Investigation</subject><subject>Patients</subject><subject>Studies</subject><subject>Thoracic surgery</subject><subject>Ultrasonic imaging</subject><issn>2149-2263</issn><issn>2149-2271</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2019</creationdate><recordtype>article</recordtype><sourceid>8G5</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><sourceid>GUQSH</sourceid><sourceid>M2O</sourceid><recordid>eNpdkUtLAzEUhYMoVtS_IEE3blrzmsRxIUjxieBG3YZMHm0kndRkpuK_N7VarJvcXPLdw7k5ABxjNMJMMHZ21aouhoexSsbHMCII1yPCCaNbYI9gVg8JEXh7fed0AA5zfkMIYUHPMea7YEBRTRFj1R54vfOTqU2wD11Szi_PzscWlmKhz1DlHLUvjYEfvpvCVPAOLmzbJa_7oBKcWT1VrdcqQOPz3KZc5g_AjlMh28Ofug9ebq6fx3fDx6fb-_HV41DTWnTDijmhnaAYGURZcWREbU3DnG1Mw5HlFGmFCHPIUKdMLZhqnOGEkEZbVFV0H1yudOd9M7NGL32pIOfJz1T6lFF5ufnS-qmcxIXkFTmvECkCpz8CKb73Nndy5rO2IajWxj5LUv5X4AozWtCTf-hb7FNb1itUJXiNqeCFulhROsWck3VrMxjJ7wTlZoJymaD8TrAMH_1dZz36mxf9AkCMngI</recordid><startdate>20190401</startdate><enddate>20190401</enddate><creator>Ünlü, Serkan</creator><creator>Pagourelias, Efstathios</creator><creator>Sezenöz, Burak</creator><creator>Şahinarslan, Asife</creator><creator>Uludağ, Orhan Mecit</creator><creator>Gökalp, Gökhan</creator><creator>Arınsoy, Turgay</creator><creator>Çengel, Atiye</creator><general>Kare Publishing</general><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>8G5</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>EDSIH</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>GUQSH</scope><scope>K9.</scope><scope>M0S</scope><scope>M1P</scope><scope>M2O</scope><scope>MBDVC</scope><scope>PADUT</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>Q9U</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>20190401</creationdate><title>Higher ultrafiltration rate is associated with right ventricular mechanical dispersion</title><author>Ünlü, Serkan ; Pagourelias, Efstathios ; Sezenöz, Burak ; Şahinarslan, Asife ; Uludağ, Orhan Mecit ; Gökalp, Gökhan ; Arınsoy, Turgay ; Çengel, Atiye</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c397t-54f7cf7310d034044d79edb4febdb60e630ca024f0d3fad974abfd6222bce0553</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2019</creationdate><topic>Cardiology</topic><topic>Cardiovascular disease</topic><topic>Clinical trials</topic><topic>Heart failure</topic><topic>Hemodialysis</topic><topic>Ischemia</topic><topic>Mortality</topic><topic>Original Investigation</topic><topic>Patients</topic><topic>Studies</topic><topic>Thoracic surgery</topic><topic>Ultrasonic imaging</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Ünlü, Serkan</creatorcontrib><creatorcontrib>Pagourelias, Efstathios</creatorcontrib><creatorcontrib>Sezenöz, Burak</creatorcontrib><creatorcontrib>Şahinarslan, Asife</creatorcontrib><creatorcontrib>Uludağ, Orhan Mecit</creatorcontrib><creatorcontrib>Gökalp, Gökhan</creatorcontrib><creatorcontrib>Arınsoy, Turgay</creatorcontrib><creatorcontrib>Çengel, Atiye</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>Research Library (Alumni Edition)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Turkey Database</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>Research Library Prep</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Research Library</collection><collection>Research Library (Corporate)</collection><collection>Research Library China</collection><collection>Access via ProQuest (Open Access)</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>ProQuest Central Basic</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Anatolian journal of cardiology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Ünlü, Serkan</au><au>Pagourelias, Efstathios</au><au>Sezenöz, Burak</au><au>Şahinarslan, Asife</au><au>Uludağ, Orhan Mecit</au><au>Gökalp, Gökhan</au><au>Arınsoy, Turgay</au><au>Çengel, Atiye</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Higher ultrafiltration rate is associated with right ventricular mechanical dispersion</atitle><jtitle>Anatolian journal of cardiology</jtitle><addtitle>Anatol J Cardiol</addtitle><date>2019-04-01</date><risdate>2019</risdate><volume>21</volume><issue>4</issue><spage>206</spage><epage>213</epage><pages>206-213</pages><issn>2149-2263</issn><eissn>2149-2271</eissn><abstract>Ultrafiltration rate is one of the major determinants of adverse outcomes in patients undergoing hemodialysis (HD) therapy. Previous studies have focused on the impact of HD on right ventricular (RV) peak strain values. However, the influence of HD on the temporal characteristics of deformation has not been reported yet. The aim of the present study was to evaluate the impact of high ultrafiltration rate (HUR) on RV mechanical dyssynchrony.
Echocardiographic images focused on the RV and left ventricle (LV) were obtained from 60 patients (49.2+-17.3 years, 22 female) before and after HD. Patients were divided into two groups according to ultrafiltration rate. Changes in echocardiographic parameters with HD were examined. Two-dimensional speckle-tracking strain analysis was used to assess deformation. Mechanical dispersion was measured as the standard deviation of time to peak longitudinal strain of six segments for RV and 18 segments for LV.
The average ultrafiltrated volume and ultrafiltration rate were 3000.1+-1007.9 mL and 11.4+-2.9 mL/kg/h, respectively. Global longitudinal strain (GLS) of the RV and LV decreased after HD in both groups. A significant difference was observed in RV mechanical dispersion with HD for patients in the high ultrafiltration group. A mild statistically insignificant increase in LV mechanical dispersion was also observed after HD.
HUR has a substantial impact on LV and RV GLS and RV dyssynchrony. Ultrafiltration rates and volumes should be kept as low as possible to achieve hemodynamic stability and tolerability.</abstract><cop>Turkey</cop><pub>Kare Publishing</pub><pmid>30930445</pmid><doi>10.14744/AnatolJCardiol.2019.26243</doi><tpages>8</tpages><oa>free_for_read</oa></addata></record> |
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| source | DOAJ Directory of Open Access Journals; EZB-FREE-00999 freely available EZB journals; PubMed Central |
| subjects | Cardiology Cardiovascular disease Clinical trials Heart failure Hemodialysis Ischemia Mortality Original Investigation Patients Studies Thoracic surgery Ultrasonic imaging |
| title | Higher ultrafiltration rate is associated with right ventricular mechanical dispersion |
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