ATP-Independent Bioluminescent Reporter Variants To Improve in Vivo Imaging

Coelenterazine (CTZ)-utilizing marine luciferases and their derivatives have attracted significant attention because of their ATP-independency, fast enzymatic turnover, and high bioluminescence brightness. However, marine luciferases typically emit blue photons and their substrates, including CTZ an...

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Veröffentlicht in:	ACS chemical biology 2019-05, Vol.14 (5), p.959-965
Hauptverfasser:	Yeh, Hsien-Wei, Xiong, Ying, Wu, Tianchen, Chen, Minghai, Ji, Ao, Li, Xinyu, Ai, Hui-wang
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenosine Triphosphate - metabolism Animals Directed Molecular Evolution Genes, Reporter Heterografts Humans Luminescence Mice
Online-Zugang:	Volltext
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