TGF-β prevents the denervation-induced reduction of bone formation and promotes the bone regeneration through inhibiting ubiquitin-proteasome pathway

Transforming growth factor beta (TGF-β) can stimulate osteogenesis as a multifunctional protein. The present study was to explore if TGF-β can prevent denervation-induced reduction of bone formation. The 6-week-old male mice were treated with recombinant human TGF-β1 (rhTGF-β1). Bone formation, endo...

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Veröffentlicht in:Bioscience reports 2019-05, Vol.39 (5)
Hauptverfasser: Yu, Zhen, Li, Ye, Wang, Yining, Chen, Yuting, Wu, Mengfan, Wang, Zijue, Song, Minkai, Lu, Feng, Lu, Xiaohe, Dong, Ziqing
Format: Artikel
Sprache:eng
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