Sleep Duration is Inversely Associated with Serum Uric Acid Concentrations and Uric Acid to Creatinine Ratio in an Elderly Mediterranean Population at High Cardiovascular Risk
The aim of the study was to evaluate sleep duration and sleep variability in relation to serum uric acid (SUA) concentrations and SUA to creatinine ratio. This is a cross-sectional analysis of baseline data from 1842 elderly participants with overweight/obesity and metabolic syndromein the (Prevenci...
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| Veröffentlicht in: | Nutrients 2019-04, Vol.11 (4), p.761 |
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| creator | Papandreou, Christopher Babio, Nancy Díaz-López, Andrés Martínez-González, Miguel Á Becerra-Tomas, Nerea Corella, Dolores Schröder, Helmut Romaguera, Dora Vioque, Jesús Alonso-Gómez, Ángel M Wärnberg, Julia Martínez, Alfredo J Serra-Majem, Lluís Estruch, Ramon Muñoz-Garach, Araceli Lapetra, José Pintó, Xavier Tur, Josep A Garcia-Rios, Antonio Bueno-Cavanillas, Aurora Delgado-Rodríguez, Miguel Matía-Martín, Pilar Daimiel, Lidia M Sánchez, Vicente Vidal, Josep Vázquez, Clotilde Ros, Emilio Ruiz-Canela, Miguel Bulló, Mónica Sorli, Jose V Quifer, Mireia Colom, Antoni Oncina-Canovas, Alejandro T Sierra, Lucas Barón-López, Javier Pérez-Farinós, Napoleón Abete, Itziar Sanchez-Villegas, Almudena Casas, Rosa F García, José C Santos-Lozano, José M Corbella, Emili Del M Bibiloni, Maria Diez-Espino, Javier Asensio, Eva M Torras, Laura Morey, Marga Compañ-Gabucio, Laura S Lete, Itziar Cenoz-Osinaga, Juan C Castañer, Olga Salas-Salvadó, Jordi |
| description | The aim of the study was to evaluate sleep duration and sleep variability in relation to serum uric acid (SUA) concentrations and SUA to creatinine ratio. This is a cross-sectional analysis of baseline data from 1842 elderly participants with overweight/obesity and metabolic syndromein the (Prevención con Dieta Mediterránea) PREDIMED-Plus trial. Accelerometry-derived sleep duration and sleep variability were measured. Linear regression models were fitted to examine the aforementioned associations. A 1 hour/night increment in sleep duration was inversely associated with SUA concentrations (β = 0.07, p = 0.047). Further adjustment for leukocytes attenuated this association (p = 0.050). Each 1-hour increment in sleep duration was inversely associated with SUA to creatinine ratio (β = 0.15, p = 0.001). The findings of this study suggest that longer sleep duration is associated with lower SUA concentrations and lower SUA to creatinine ratio. |
| doi_str_mv | 10.3390/nu11040761 |
| format | Article |
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This is a cross-sectional analysis of baseline data from 1842 elderly participants with overweight/obesity and metabolic syndromein the (Prevención con Dieta Mediterránea) PREDIMED-Plus trial. Accelerometry-derived sleep duration and sleep variability were measured. Linear regression models were fitted to examine the aforementioned associations. A 1 hour/night increment in sleep duration was inversely associated with SUA concentrations (β = 0.07, p = 0.047). Further adjustment for leukocytes attenuated this association (p = 0.050). Each 1-hour increment in sleep duration was inversely associated with SUA to creatinine ratio (β = 0.15, p = 0.001). The findings of this study suggest that longer sleep duration is associated with lower SUA concentrations and lower SUA to creatinine ratio.</description><identifier>ISSN: 2072-6643</identifier><identifier>EISSN: 2072-6643</identifier><identifier>DOI: 10.3390/nu11040761</identifier><identifier>PMID: 30939748</identifier><language>eng</language><publisher>Switzerland: MDPI AG</publisher><subject>Blood pressure ; blood serum ; Body mass index ; Byproducts ; Cardiovascular diseases ; Communication ; Creatinine ; cross-sectional studies ; Diabetes ; elderly ; Endocrinology ; Epidemiology ; Fasting ; Geriatrics ; Health care ; Health risks ; Health sciences ; Hospitals ; Internal medicine ; leukocytes ; Life expectancy ; Medical research ; Metabolic disorders ; Metabolic syndrome ; Nutrition research ; obesity ; Older people ; Preventive medicine ; Public health ; Purines ; regression analysis ; Research centers ; Sleep ; Sleep apnea ; Uric acid</subject><ispartof>Nutrients, 2019-04, Vol.11 (4), p.761</ispartof><rights>2019. This work is licensed under https://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><rights>2019 by the authors. 2019</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c439t-826f79121a43f7d732fbd8796d2191bc1b9eda99402ef8e849fa38b07e8d58573</citedby><cites>FETCH-LOGICAL-c439t-826f79121a43f7d732fbd8796d2191bc1b9eda99402ef8e849fa38b07e8d58573</cites><orcidid>0000-0002-3917-9808 ; 0000-0002-0130-2006 ; 0000-0003-3169-997X ; 0000-0002-6803-507X ; 0000-0002-6475-5387 ; 0000-0003-2229-8488 ; 0000-0002-9658-9061 ; 0000-0002-2366-4104 ; 0000-0002-2284-148X ; 0000-0003-2945-7509 ; 0000-0001-7936-1172 ; 0000-0001-5218-6941 ; 0000-0002-6940-0761 ; 0000-0002-4429-6507 ; 0000-0002-7684-2787 ; 0000-0002-1867-1158 ; 0000-0002-0218-7046 ; 0000-0003-2700-7459 ; 0000-0002-0649-3016 ; 0000-0002-2573-1294 ; 0000-0001-9898-6629 ; 0000-0002-8408-316X ; 0000-0003-1629-2143 ; 0000-0003-3527-5277 ; 0000-0001-5041-0778 ; 0000-0002-5762-8558 ; 0000-0002-0211-9166 ; 0000-0003-0552-2804</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC6521014/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC6521014/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,723,776,780,881,27901,27902,53766,53768</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/30939748$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Papandreou, Christopher</creatorcontrib><creatorcontrib>Babio, Nancy</creatorcontrib><creatorcontrib>Díaz-López, Andrés</creatorcontrib><creatorcontrib>Martínez-González, Miguel Á</creatorcontrib><creatorcontrib>Becerra-Tomas, Nerea</creatorcontrib><creatorcontrib>Corella, Dolores</creatorcontrib><creatorcontrib>Schröder, Helmut</creatorcontrib><creatorcontrib>Romaguera, Dora</creatorcontrib><creatorcontrib>Vioque, Jesús</creatorcontrib><creatorcontrib>Alonso-Gómez, Ángel M</creatorcontrib><creatorcontrib>Wärnberg, Julia</creatorcontrib><creatorcontrib>Martínez, Alfredo J</creatorcontrib><creatorcontrib>Serra-Majem, Lluís</creatorcontrib><creatorcontrib>Estruch, Ramon</creatorcontrib><creatorcontrib>Muñoz-Garach, Araceli</creatorcontrib><creatorcontrib>Lapetra, José</creatorcontrib><creatorcontrib>Pintó, Xavier</creatorcontrib><creatorcontrib>Tur, Josep A</creatorcontrib><creatorcontrib>Garcia-Rios, Antonio</creatorcontrib><creatorcontrib>Bueno-Cavanillas, Aurora</creatorcontrib><creatorcontrib>Delgado-Rodríguez, Miguel</creatorcontrib><creatorcontrib>Matía-Martín, Pilar</creatorcontrib><creatorcontrib>Daimiel, Lidia</creatorcontrib><creatorcontrib>M Sánchez, Vicente</creatorcontrib><creatorcontrib>Vidal, Josep</creatorcontrib><creatorcontrib>Vázquez, Clotilde</creatorcontrib><creatorcontrib>Ros, Emilio</creatorcontrib><creatorcontrib>Ruiz-Canela, Miguel</creatorcontrib><creatorcontrib>Bulló, Mónica</creatorcontrib><creatorcontrib>Sorli, Jose V</creatorcontrib><creatorcontrib>Quifer, Mireia</creatorcontrib><creatorcontrib>Colom, Antoni</creatorcontrib><creatorcontrib>Oncina-Canovas, Alejandro</creatorcontrib><creatorcontrib>T Sierra, Lucas</creatorcontrib><creatorcontrib>Barón-López, Javier</creatorcontrib><creatorcontrib>Pérez-Farinós, Napoleón</creatorcontrib><creatorcontrib>Abete, Itziar</creatorcontrib><creatorcontrib>Sanchez-Villegas, Almudena</creatorcontrib><creatorcontrib>Casas, Rosa</creatorcontrib><creatorcontrib>F García, José C</creatorcontrib><creatorcontrib>Santos-Lozano, José M</creatorcontrib><creatorcontrib>Corbella, Emili</creatorcontrib><creatorcontrib>Del M Bibiloni, Maria</creatorcontrib><creatorcontrib>Diez-Espino, Javier</creatorcontrib><creatorcontrib>Asensio, Eva M</creatorcontrib><creatorcontrib>Torras, Laura</creatorcontrib><creatorcontrib>Morey, Marga</creatorcontrib><creatorcontrib>Compañ-Gabucio, Laura</creatorcontrib><creatorcontrib>S Lete, Itziar</creatorcontrib><creatorcontrib>Cenoz-Osinaga, Juan C</creatorcontrib><creatorcontrib>Castañer, Olga</creatorcontrib><creatorcontrib>Salas-Salvadó, Jordi</creatorcontrib><title>Sleep Duration is Inversely Associated with Serum Uric Acid Concentrations and Uric Acid to Creatinine Ratio in an Elderly Mediterranean Population at High Cardiovascular Risk</title><title>Nutrients</title><addtitle>Nutrients</addtitle><description>The aim of the study was to evaluate sleep duration and sleep variability in relation to serum uric acid (SUA) concentrations and SUA to creatinine ratio. This is a cross-sectional analysis of baseline data from 1842 elderly participants with overweight/obesity and metabolic syndromein the (Prevención con Dieta Mediterránea) PREDIMED-Plus trial. Accelerometry-derived sleep duration and sleep variability were measured. Linear regression models were fitted to examine the aforementioned associations. A 1 hour/night increment in sleep duration was inversely associated with SUA concentrations (β = 0.07, p = 0.047). Further adjustment for leukocytes attenuated this association (p = 0.050). Each 1-hour increment in sleep duration was inversely associated with SUA to creatinine ratio (β = 0.15, p = 0.001). The findings of this study suggest that longer sleep duration is associated with lower SUA concentrations and lower SUA to creatinine ratio.</description><subject>Blood pressure</subject><subject>blood serum</subject><subject>Body mass index</subject><subject>Byproducts</subject><subject>Cardiovascular diseases</subject><subject>Communication</subject><subject>Creatinine</subject><subject>cross-sectional studies</subject><subject>Diabetes</subject><subject>elderly</subject><subject>Endocrinology</subject><subject>Epidemiology</subject><subject>Fasting</subject><subject>Geriatrics</subject><subject>Health care</subject><subject>Health risks</subject><subject>Health sciences</subject><subject>Hospitals</subject><subject>Internal medicine</subject><subject>leukocytes</subject><subject>Life expectancy</subject><subject>Medical research</subject><subject>Metabolic disorders</subject><subject>Metabolic syndrome</subject><subject>Nutrition research</subject><subject>obesity</subject><subject>Older people</subject><subject>Preventive medicine</subject><subject>Public health</subject><subject>Purines</subject><subject>regression analysis</subject><subject>Research centers</subject><subject>Sleep</subject><subject>Sleep apnea</subject><subject>Uric 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Duration is Inversely Associated with Serum Uric Acid Concentrations and Uric Acid to Creatinine Ratio in an Elderly Mediterranean Population at High Cardiovascular Risk</title><author>Papandreou, Christopher ; Babio, Nancy ; Díaz-López, Andrés ; Martínez-González, Miguel Á ; Becerra-Tomas, Nerea ; Corella, Dolores ; Schröder, Helmut ; Romaguera, Dora ; Vioque, Jesús ; Alonso-Gómez, Ángel M ; Wärnberg, Julia ; Martínez, Alfredo J ; Serra-Majem, Lluís ; Estruch, Ramon ; Muñoz-Garach, Araceli ; Lapetra, José ; Pintó, Xavier ; Tur, Josep A ; Garcia-Rios, Antonio ; Bueno-Cavanillas, Aurora ; Delgado-Rodríguez, Miguel ; Matía-Martín, Pilar ; Daimiel, Lidia ; M Sánchez, Vicente ; Vidal, Josep ; Vázquez, Clotilde ; Ros, Emilio ; Ruiz-Canela, Miguel ; Bulló, Mónica ; Sorli, Jose V ; Quifer, Mireia ; Colom, Antoni ; Oncina-Canovas, Alejandro ; T Sierra, Lucas ; Barón-López, Javier ; Pérez-Farinós, Napoleón ; Abete, Itziar ; Sanchez-Villegas, Almudena ; Casas, Rosa ; F García, José C ; Santos-Lozano, José M ; Corbella, Emili ; Del M Bibiloni, Maria ; Diez-Espino, Javier ; Asensio, Eva M ; Torras, Laura ; Morey, Marga ; Compañ-Gabucio, Laura ; S Lete, Itziar ; Cenoz-Osinaga, Juan C ; Castañer, Olga ; Salas-Salvadó, Jordi</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c439t-826f79121a43f7d732fbd8796d2191bc1b9eda99402ef8e849fa38b07e8d58573</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2019</creationdate><topic>Blood pressure</topic><topic>blood serum</topic><topic>Body mass index</topic><topic>Byproducts</topic><topic>Cardiovascular diseases</topic><topic>Communication</topic><topic>Creatinine</topic><topic>cross-sectional studies</topic><topic>Diabetes</topic><topic>elderly</topic><topic>Endocrinology</topic><topic>Epidemiology</topic><topic>Fasting</topic><topic>Geriatrics</topic><topic>Health care</topic><topic>Health risks</topic><topic>Health sciences</topic><topic>Hospitals</topic><topic>Internal medicine</topic><topic>leukocytes</topic><topic>Life expectancy</topic><topic>Medical research</topic><topic>Metabolic disorders</topic><topic>Metabolic syndrome</topic><topic>Nutrition research</topic><topic>obesity</topic><topic>Older people</topic><topic>Preventive medicine</topic><topic>Public health</topic><topic>Purines</topic><topic>regression analysis</topic><topic>Research centers</topic><topic>Sleep</topic><topic>Sleep apnea</topic><topic>Uric acid</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Papandreou, Christopher</creatorcontrib><creatorcontrib>Babio, Nancy</creatorcontrib><creatorcontrib>Díaz-López, Andrés</creatorcontrib><creatorcontrib>Martínez-González, Miguel Á</creatorcontrib><creatorcontrib>Becerra-Tomas, Nerea</creatorcontrib><creatorcontrib>Corella, Dolores</creatorcontrib><creatorcontrib>Schröder, Helmut</creatorcontrib><creatorcontrib>Romaguera, Dora</creatorcontrib><creatorcontrib>Vioque, Jesús</creatorcontrib><creatorcontrib>Alonso-Gómez, Ángel M</creatorcontrib><creatorcontrib>Wärnberg, Julia</creatorcontrib><creatorcontrib>Martínez, Alfredo J</creatorcontrib><creatorcontrib>Serra-Majem, Lluís</creatorcontrib><creatorcontrib>Estruch, Ramon</creatorcontrib><creatorcontrib>Muñoz-Garach, Araceli</creatorcontrib><creatorcontrib>Lapetra, José</creatorcontrib><creatorcontrib>Pintó, Xavier</creatorcontrib><creatorcontrib>Tur, Josep A</creatorcontrib><creatorcontrib>Garcia-Rios, Antonio</creatorcontrib><creatorcontrib>Bueno-Cavanillas, Aurora</creatorcontrib><creatorcontrib>Delgado-Rodríguez, Miguel</creatorcontrib><creatorcontrib>Matía-Martín, Pilar</creatorcontrib><creatorcontrib>Daimiel, Lidia</creatorcontrib><creatorcontrib>M Sánchez, Vicente</creatorcontrib><creatorcontrib>Vidal, Josep</creatorcontrib><creatorcontrib>Vázquez, Clotilde</creatorcontrib><creatorcontrib>Ros, Emilio</creatorcontrib><creatorcontrib>Ruiz-Canela, Miguel</creatorcontrib><creatorcontrib>Bulló, Mónica</creatorcontrib><creatorcontrib>Sorli, Jose V</creatorcontrib><creatorcontrib>Quifer, Mireia</creatorcontrib><creatorcontrib>Colom, Antoni</creatorcontrib><creatorcontrib>Oncina-Canovas, Alejandro</creatorcontrib><creatorcontrib>T Sierra, Lucas</creatorcontrib><creatorcontrib>Barón-López, Javier</creatorcontrib><creatorcontrib>Pérez-Farinós, Napoleón</creatorcontrib><creatorcontrib>Abete, Itziar</creatorcontrib><creatorcontrib>Sanchez-Villegas, Almudena</creatorcontrib><creatorcontrib>Casas, Rosa</creatorcontrib><creatorcontrib>F García, José C</creatorcontrib><creatorcontrib>Santos-Lozano, José M</creatorcontrib><creatorcontrib>Corbella, Emili</creatorcontrib><creatorcontrib>Del M Bibiloni, Maria</creatorcontrib><creatorcontrib>Diez-Espino, Javier</creatorcontrib><creatorcontrib>Asensio, Eva M</creatorcontrib><creatorcontrib>Torras, Laura</creatorcontrib><creatorcontrib>Morey, Marga</creatorcontrib><creatorcontrib>Compañ-Gabucio, Laura</creatorcontrib><creatorcontrib>S Lete, Itziar</creatorcontrib><creatorcontrib>Cenoz-Osinaga, Juan C</creatorcontrib><creatorcontrib>Castañer, Olga</creatorcontrib><creatorcontrib>Salas-Salvadó, Jordi</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Physical Education Index</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Publicly Available Content Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>MEDLINE - Academic</collection><collection>AGRICOLA</collection><collection>AGRICOLA - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Nutrients</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Papandreou, Christopher</au><au>Babio, Nancy</au><au>Díaz-López, Andrés</au><au>Martínez-González, Miguel Á</au><au>Becerra-Tomas, Nerea</au><au>Corella, Dolores</au><au>Schröder, Helmut</au><au>Romaguera, Dora</au><au>Vioque, Jesús</au><au>Alonso-Gómez, Ángel M</au><au>Wärnberg, Julia</au><au>Martínez, Alfredo J</au><au>Serra-Majem, Lluís</au><au>Estruch, Ramon</au><au>Muñoz-Garach, Araceli</au><au>Lapetra, José</au><au>Pintó, Xavier</au><au>Tur, Josep A</au><au>Garcia-Rios, Antonio</au><au>Bueno-Cavanillas, Aurora</au><au>Delgado-Rodríguez, Miguel</au><au>Matía-Martín, Pilar</au><au>Daimiel, Lidia</au><au>M Sánchez, Vicente</au><au>Vidal, Josep</au><au>Vázquez, Clotilde</au><au>Ros, Emilio</au><au>Ruiz-Canela, Miguel</au><au>Bulló, Mónica</au><au>Sorli, Jose V</au><au>Quifer, Mireia</au><au>Colom, Antoni</au><au>Oncina-Canovas, Alejandro</au><au>T Sierra, Lucas</au><au>Barón-López, Javier</au><au>Pérez-Farinós, Napoleón</au><au>Abete, Itziar</au><au>Sanchez-Villegas, Almudena</au><au>Casas, Rosa</au><au>F García, José C</au><au>Santos-Lozano, José M</au><au>Corbella, Emili</au><au>Del M Bibiloni, Maria</au><au>Diez-Espino, Javier</au><au>Asensio, Eva M</au><au>Torras, Laura</au><au>Morey, Marga</au><au>Compañ-Gabucio, Laura</au><au>S Lete, Itziar</au><au>Cenoz-Osinaga, Juan C</au><au>Castañer, Olga</au><au>Salas-Salvadó, Jordi</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Sleep Duration is Inversely Associated with Serum Uric Acid Concentrations and Uric Acid to Creatinine Ratio in an Elderly Mediterranean Population at High Cardiovascular Risk</atitle><jtitle>Nutrients</jtitle><addtitle>Nutrients</addtitle><date>2019-04-01</date><risdate>2019</risdate><volume>11</volume><issue>4</issue><spage>761</spage><pages>761-</pages><issn>2072-6643</issn><eissn>2072-6643</eissn><abstract>The aim of the study was to evaluate sleep duration and sleep variability in relation to serum uric acid (SUA) concentrations and SUA to creatinine ratio. This is a cross-sectional analysis of baseline data from 1842 elderly participants with overweight/obesity and metabolic syndromein the (Prevención con Dieta Mediterránea) PREDIMED-Plus trial. Accelerometry-derived sleep duration and sleep variability were measured. Linear regression models were fitted to examine the aforementioned associations. A 1 hour/night increment in sleep duration was inversely associated with SUA concentrations (β = 0.07, p = 0.047). Further adjustment for leukocytes attenuated this association (p = 0.050). Each 1-hour increment in sleep duration was inversely associated with SUA to creatinine ratio (β = 0.15, p = 0.001). The findings of this study suggest that longer sleep duration is associated with lower SUA concentrations and lower SUA to creatinine ratio.</abstract><cop>Switzerland</cop><pub>MDPI AG</pub><pmid>30939748</pmid><doi>10.3390/nu11040761</doi><orcidid>https://orcid.org/0000-0002-3917-9808</orcidid><orcidid>https://orcid.org/0000-0002-0130-2006</orcidid><orcidid>https://orcid.org/0000-0003-3169-997X</orcidid><orcidid>https://orcid.org/0000-0002-6803-507X</orcidid><orcidid>https://orcid.org/0000-0002-6475-5387</orcidid><orcidid>https://orcid.org/0000-0003-2229-8488</orcidid><orcidid>https://orcid.org/0000-0002-9658-9061</orcidid><orcidid>https://orcid.org/0000-0002-2366-4104</orcidid><orcidid>https://orcid.org/0000-0002-2284-148X</orcidid><orcidid>https://orcid.org/0000-0003-2945-7509</orcidid><orcidid>https://orcid.org/0000-0001-7936-1172</orcidid><orcidid>https://orcid.org/0000-0001-5218-6941</orcidid><orcidid>https://orcid.org/0000-0002-6940-0761</orcidid><orcidid>https://orcid.org/0000-0002-4429-6507</orcidid><orcidid>https://orcid.org/0000-0002-7684-2787</orcidid><orcidid>https://orcid.org/0000-0002-1867-1158</orcidid><orcidid>https://orcid.org/0000-0002-0218-7046</orcidid><orcidid>https://orcid.org/0000-0003-2700-7459</orcidid><orcidid>https://orcid.org/0000-0002-0649-3016</orcidid><orcidid>https://orcid.org/0000-0002-2573-1294</orcidid><orcidid>https://orcid.org/0000-0001-9898-6629</orcidid><orcidid>https://orcid.org/0000-0002-8408-316X</orcidid><orcidid>https://orcid.org/0000-0003-1629-2143</orcidid><orcidid>https://orcid.org/0000-0003-3527-5277</orcidid><orcidid>https://orcid.org/0000-0001-5041-0778</orcidid><orcidid>https://orcid.org/0000-0002-5762-8558</orcidid><orcidid>https://orcid.org/0000-0002-0211-9166</orcidid><orcidid>https://orcid.org/0000-0003-0552-2804</orcidid><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 2072-6643 |
| ispartof | Nutrients, 2019-04, Vol.11 (4), p.761 |
| issn | 2072-6643 2072-6643 |
| language | eng |
| recordid | cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6521014 |
| source | MDPI - Multidisciplinary Digital Publishing Institute; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; PubMed Central; PubMed Central Open Access |
| subjects | Blood pressure blood serum Body mass index Byproducts Cardiovascular diseases Communication Creatinine cross-sectional studies Diabetes elderly Endocrinology Epidemiology Fasting Geriatrics Health care Health risks Health sciences Hospitals Internal medicine leukocytes Life expectancy Medical research Metabolic disorders Metabolic syndrome Nutrition research obesity Older people Preventive medicine Public health Purines regression analysis Research centers Sleep Sleep apnea Uric acid |
| title | Sleep Duration is Inversely Associated with Serum Uric Acid Concentrations and Uric Acid to Creatinine Ratio in an Elderly Mediterranean Population at High Cardiovascular Risk |
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