Curcumin and o-Vanillin Exhibit Evidence of Senolytic Activity in Human IVD Cells In Vitro

Curcumin and o-Vanillin cleared senescent intervertebral disc (IVD) cells and reduced the senescence-associated secretory phenotype (SASP) associated with inflammation and back pain. Cells from degenerate and non-mildly-degenerate human IVD were obtained from organ donors and from patients undergoin...

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Veröffentlicht in:Journal of clinical medicine 2019-03, Vol.8 (4), p.433
Hauptverfasser: Cherif, Hosni, Bisson, Daniel G, Jarzem, Peter, Weber, Michael, Ouellet, Jean A, Haglund, Lisbet
Format: Artikel
Sprache:eng
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