The IL-23p19/EBI3 heterodimeric cytokine termed IL-39 remains a theoretical cytokine in man

Objective The heterodimeric IL-12 family member cytokines including, IL-12, IL-23, IL-27, and IL-35 and have multiple roles in regulating innate and adaptive immunity with crucial functions in inflammatory disorders such as psoriasis. Chain pairing promiscuity is a feature of the IL-12 family. Recen...

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Veröffentlicht in:	Inflammation research 2019-06, Vol.68 (6), p.423-426
Hauptverfasser:	Bridgewood, Charlie, Alase, Adewonuola, Watad, Abdulla, Wittmann, Miriam, Cuthbert, Richard, McGonagle, Dennis
Format:	Artikel
Sprache:	eng
Schlagworte:	Adaptive immunity Allergology Biomedical and Life Sciences Biomedicine Chains Cytokines Dermatology Immunity Immunology Inflammatory diseases Interleukin 12 Interleukin 23 Interleukin 27 Interleukin 6 Interleukin 8 Leukocytes Neurology Pharmacology/Toxicology Phosphorylation Proteins Psoriasis Rheumatology Short Communication Stat3 protein Therapeutic targets Tumor necrosis factor
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