Differential microglia and macrophage profiles in human IDH-mutant and -wild type glioblastoma

Microglia and macrophages are the largest component of the inflammatory infiltrate in glioblastoma (GBM). However, whether there are differences in their representation and activity in the prognostically-favorable isocitrate dehydrogenase (IDH)-mutated compared to -wild type GBMs is unknown. Studies...

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Veröffentlicht in:Oncotarget 2019-05, Vol.10 (33), p.3129-3143
Hauptverfasser: Poon, Candice C, Gordon, Paul M K, Liu, Katherine, Yang, Runze, Sarkar, Susobhan, Mirzaei, Reza, Ahmad, Shiekh Tanveer, Hughes, Martha L, Yong, V Wee, Kelly, John J P
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