Centella asiatica Protects d-Galactose/AlCl3 Mediated Alzheimer’s Disease-Like Rats via PP2A/GSK-3β Signaling Pathway in Their Hippocampus

Alzheimer’s disease (AD) is a progressive neurodegenerative disorder more prevalent among the elderly population. AD is characterised clinically by a progressive decline in cognitive functions and pathologically by the presence of neurofibrillary tangles (NFTs), deposition of beta-amyloid (Aβ) plaqu...

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Veröffentlicht in:	International journal of molecular sciences 2019-04, Vol.20 (8), p.1871
Hauptverfasser:	Chiroma, Samaila Musa, Baharuldin, Mohamad Taufik Hidayat, Mat Taib, Che Norma, Amom, Zulkhairi, Jagadeesan, Saravanan, Ilham Adenan, Mohd, Mahdi, Onesimus, Moklas, Mohamad Aris Mohd
Format:	Artikel
Sprache:	eng
Schlagworte:	Abnormalities Aging Aging (artificial) Aluminum chloride Alzheimer's disease Animal cognition Apoptosis Brain Cholinergics Cognitive ability D-Galactose Drug screening Galactose Hippocampus Kinases Memory Mitochondria Morphology Neurodegeneration Neurofibrillary tangles Neurotoxicity Nucleoli Oxidative stress Pathogenesis Phosphatase Phosphorylation Proteins Pyramidal cells Rodents Signal transduction Statistical analysis Studies β-Amyloid
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