Association of Intravitreal Anti–Vascular Endothelial Growth Factor Therapy With Risk of Stroke, Myocardial Infarction, and Death in Patients With Exudative Age-Related Macular Degeneration

IMPORTANCE: Current studies assessing the risk of stroke, myocardial infarction (MI), and death in patients undergoing intravitreal anti–vascular endothelial growth factor (VEGF) therapy are inconclusive. To our knowledge, no population-based studies have been performed to examine these potential ri...

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Veröffentlicht in:	Archives of ophthalmology (1960) 2019-05, Vol.137 (5), p.483-490
Hauptverfasser:	Dalvin, Lauren A, Starr, Matthew R, AbouChehade, Jackson E, Damento, Gena M, Garcia, Maria, Shah, Saumya M, Hodge, David O, Meissner, Irene, Bakri, Sophie J, Iezzi, Raymond
Format:	Artikel
Sprache:	eng
Schlagworte:	Age Aged Aptamers, Nucleotide - administration & dosage Aptamers, Nucleotide - adverse effects Cause of Death - trends Cerebral infarction Death Dose-Response Relationship, Drug Epidemiology Female Follow-Up Studies Heart attacks Humans Injection Intravitreal Injections - adverse effects Macula Lutea - pathology Macular degeneration Male Minnesota - epidemiology Multivariate analysis Myocardial infarction Myocardial Infarction - epidemiology Myocardial Infarction - etiology Online First Ophthalmology Original Investigation Population studies Prognosis Regression analysis Retrospective Studies Risk Assessment - methods Risk Factors Stroke Stroke - epidemiology Stroke - etiology Survival Rate - trends Time Factors Tomography, Optical Coherence - methods Vascular endothelial growth factor Vascular Endothelial Growth Factor A - antagonists & inhibitors Wet Macular Degeneration - complications Wet Macular Degeneration - drug therapy Wet Macular Degeneration - mortality
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