Synthesis and Automated Labeling of [18F]Darapladib, a Lp-PLA2 Ligand, as Potential PET Imaging Tool of Atherosclerosis

Atherosclerosis and its associated clinical complications are major health issues in industrialized countries. Lipoprotein-associated phospholipase A2 (Lp-PLA2) was demonstrated to play an important role in atherogenesis and to be a potential risk prediction factor of plaque rupture. Darapladib is o...

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Veröffentlicht in:	ACS medicinal chemistry letters 2019-05, Vol.10 (5), p.743-748
Hauptverfasser:	Guibbal, Florian, Meneyrol, Vincent, Ait-Arsa, Imade, Diotel, Nicolas, Patché, Jessica, Veeren, Bryan, Bénard, Sébastien, Gimié, Fanny, Yong-Sang, Jennyfer, Khantalin, Ilya, Veerapen, Reuben, Jestin, Emmanuelle, Meilhac, Olivier
Format:	Artikel
Sprache:	eng
Schlagworte:	Letter
Online-Zugang:	Volltext
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