Epithelial-Mesenchymal Plasticity in Cancer Progression and Metastasis

Epithelial-to-mesenchymal transition (EMT) and its reversed process, mesenchymal-to-epithelial transition (MET), are fundamental processes in embryonic development and tissue repair but confer malignant properties to carcinoma cells, including invasive behavior, cancer stem cell activity, and greate...

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Veröffentlicht in:	Developmental cell 2019-05, Vol.49 (3), p.361-374
Hauptverfasser:	Lu, Wei, Kang, Yibin
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cell Plasticity - physiology Cell Transformation, Neoplastic - pathology cellular plasticity chemoresistance Embryonic Development Epithelial-Mesenchymal Transition - physiology epithelial-to-mesenchymal transition Fibroblasts - metabolism Humans immune evasion metastasis Neoplasm Invasiveness - pathology Neoplasm Metastasis - pathology Neoplasms - metabolism Neoplasms - pathology Neoplastic Stem Cells - pathology Neovascularization, Pathologic - pathology stemness
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