Genomic profiling in pancreatic ductal adenocarcinoma and a pathway towards therapy individualization: A scoping review

•Genomic alterations in PDAC represent potential targeting opportunities to individualize therapy.•Attempts to target key somatic driver mutations in PDAC have been unsuccessful.•DNA-damage repair gene mutations confer vulnerability to platinum agents and PARP-inhibitors.•Microsatellite unstable PDA...

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