Association of p53 expression with poor prognosis in patients with triple-negative breast invasive ductal carcinoma

TP53 gene is mutated in approximately 80% of triple-negative breast cancer (TNBC). However, the prognostic significance of immunohistochemical (IHC)-detected p53 protein expression remains controversial in TNBC. In this study, we retrospectively analyzed the association between IHC-detected p53 expr...

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Veröffentlicht in:	Medicine (Baltimore) 2019-05, Vol.98 (18), p.e15449-e15449
Hauptverfasser:	Li, Jing-ping, Zhang, Xiang-mei, Zhang, Zhenzhen, Zheng, Li-hua, Jindal, Sonali, Liu, Yun-jiang
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Aged, 80 and over Biomarkers, Tumor Carcinoma, Ductal - mortality Carcinoma, Ductal - pathology Disease-Free Survival Female Genes, p53 - physiology Humans Immunohistochemistry Kaplan-Meier Estimate Middle Aged Neoplasm Grading Neoplasm Invasiveness Neoplasm Staging Observational Study Prognosis Proportional Hazards Models Retrospective Studies Triple Negative Breast Neoplasms - mortality Triple Negative Breast Neoplasms - pathology Tumor Suppressor Protein p53 - genetics
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