Two novel genes TOX3 and COL21A1 in large extended Malay families with nonsyndromic cleft lip and/or palate

Background Nonsyndromic cleft lip and/or palate is one of the most common human birth defects worldwide that affects the lip and/or palate. The incidence of clefts varies among populations through ethnic, race, or geographical differences. The focus on Malay nonsyndromic cleft lip and/or palate (NSC...

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Veröffentlicht in:	Molecular genetics & genomic medicine 2019-05, Vol.7 (5), p.e635-n/a
Hauptverfasser:	Mohamad Shah, Nurul Syazana, Sulong, Sarina, Wan Sulaiman, Wan Azman, Halim, Ahmad Sukari
Format:	Artikel
Sprache:	eng
Schlagworte:	Apoptosis Regulatory Proteins Birth defects Chromosome 4 Chromosomes Cleft Lip - genetics Cleft Lip - pathology cleft lip and/or palate Cleft lip/palate Cleft Palate - genetics Cleft Palate - pathology Congenital defects Copy number Deoxyribonucleic acid DNA DNA Copy Number Variations Female Fibrillar Collagens - genetics Genes genetic Genetic counseling Genetic testing Genomes High Mobility Group Proteins Humans linkage Linkage analysis Malaysia Male Matrix Attachment Region Binding Proteins - genetics microarray Nucleotide sequence Original Pedigree Polymerase chain reaction Proteins Receptors, Progesterone - genetics Software Statistical analysis Studies Trans-Activators Transcription Factors - genetics
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