Current opinion and mechanistic interpretation of combination therapy for castration-resistant prostate cancer

Recent advances in genomics technology have led to the massive discovery of new drug targets for prostate cancer; however, none of the currently available therapeutics is curative. One of the greatest challenges is drug resistance. Combinations of therapies with distinct mechanisms of action represe...

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Veröffentlicht in:	Asian journal of andrology 2019-05, Vol.21 (3), p.270-278
Hauptverfasser:	Xu, Jin, Qiu, Yun
Format:	Artikel
Sprache:	eng
Schlagworte:	Adrenergic mechanisms Analysis Androgen Antagonists - therapeutic use Antineoplastic Combined Chemotherapy Protocols - therapeutic use Cancer therapies Castration Combination drug therapy Combined Modality Therapy Drug resistance Drug therapy Genetic aspects Humans Invited Review Male Mechanical properties Mutation Patient outcomes Prostate cancer Prostatic Neoplasms, Castration-Resistant - drug therapy Studies
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