A Novel Fluorescent and Bioluminescent Bireporter Influenza A Virus To Evaluate Viral Infections

Studying influenza A virus (IAV) requires the use of secondary approaches to detect the presence of virus in infected cells. To overcome this problem, we and others have generated recombinant IAV expressing fluorescent or luciferase reporter genes. These foreign reporter genes can be used as valid s...

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Veröffentlicht in:	Journal of virology 2019-05, Vol.93 (10)
Hauptverfasser:	Nogales, Aitor, Ávila-Pérez, Gines, Rangel-Moreno, Javier, Chiem, Kevin, DeDiego, Marta L, Martínez-Sobrido, Luis
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antiviral Agents - pharmacology Dogs Female Genes, Reporter - drug effects Genes, Reporter - genetics Genetic Engineering - methods Genome and Regulation of Viral Gene Expression Genome, Viral - drug effects HEK293 Cells Host Microbial Interactions - physiology Humans Influenza A virus - metabolism Influenza A virus - pathogenicity Influenza, Human - genetics Luminescent Measurements - methods Luminescent Proteins - genetics Madin Darby Canine Kidney Cells Mice Mice, Inbred BALB C Optical Imaging - methods Orthomyxoviridae Infections - virology Virus Replication - drug effects
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