Comparison of endoscopic ultrasound tissue acquisition methods for genomic analysis of pancreatic cancer

Background and Aim Tumor genotyping may allow for improved prognostication and targeted therapy for pancreatic ductal adenocarcinoma (PDAC). We aimed to compare endoscopic ultrasonography (EUS) with fine needle aspiration (FNA) to fine needle biopsy (FNB) for obtaining sufficient tissue for genomic...

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Veröffentlicht in:	Journal of gastroenterology and hepatology 2019-05, Vol.34 (5), p.907-913
Hauptverfasser:	Elhanafi, Sherif, Mahmud, Nadim, Vergara, Norge, Kochman, Michael L, Das, Koushik K, Ginsberg, Gregory G, Rajala, Michael, Chandrasekhara, Vinay
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenocarcinoma Adolescent Adult Aged Biopsy Carcinoma, Pancreatic Ductal - genetics Carcinoma, Pancreatic Ductal - pathology Cellular biology Cohort Studies Cytology diagnosis Endoscopic Ultrasound-Guided Fine Needle Aspiration - methods Endoscopy Female Genomic analysis Genomics - methods Genotyping Genotyping Techniques - methods human genetics Humans Male Middle Aged Neck p53 Protein Pancreatic cancer pancreatic neoplasms Pancreatic Neoplasms - genetics Pancreatic Neoplasms - pathology Precision medicine Retrospective Studies Smad4 protein Specimen Handling Tumors Ultrasonic imaging Ultrasound Young Adult
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