Curcumin inhibits angiogenesis by up-regulation of microRNA-1275 and microRNA-1246: a promising therapy for treatment of corneal neovascularization

Objective Curcumin (capable of inhibiting angiogenic growth of human umbilical vein endothelial cells [HUVECs]), can be employed in vitro as a model of pathogenesis of corneal neovascularization (CRNV). The aim of this study was to explore regulatory mechanisms of microRNA (miR) levels after curcumi...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Cell proliferation 2016-12, Vol.49 (6), p.751-762
Hauptverfasser:	Bai, Yanhui, Wang, Weiqun, Sun, Guangli, Zhang, Mingchang, Dong, Jingmin
Format:	Artikel
Sprache:	eng
Schlagworte:	Angiogenesis Inhibitors - pharmacology Co-Repressor Proteins - genetics Corneal Neovascularization - drug therapy Corneal Neovascularization - genetics Corneal Neovascularization - pathology Curcumin - pharmacology Human Umbilical Vein Endothelial Cells Humans MicroRNAs - genetics Neovascularization, Pathologic - drug therapy Neovascularization, Pathologic - genetics Neovascularization, Pathologic - pathology Nuclear Proteins - genetics Original Up-Regulation - drug effects
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!