Tumour cell population growth inhibition and cell death induction of functionalized 6-aminoquinolone derivatives

Objectives A number of previous studies has provided evidence that the well‐known anti‐bacterial quinolones may have potential as anti‐cancer drugs. The aim of this study was to evaluate potential anti‐tumour activity and selectivity of a set of 6‐aminoquinolones showing some chemical similarity to...

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Veröffentlicht in:	Cell proliferation 2015-12, Vol.48 (6), p.705-717
Hauptverfasser:	Franci, G., Manfroni, G., Cannalire, R., Felicetti, T., Tabarrini, O., Salvato, A., Barreca, M. L., Altucci, L., Cecchetti, V.
Format:	Artikel
Sprache:	eng
Schlagworte:	Aminoquinolines - chemical synthesis Aminoquinolines - pharmacology Antineoplastic Agents - pharmacology Apoptosis - drug effects Benzothiazoles - pharmacology Breast Neoplasms - drug therapy Cell Cycle - drug effects Cell Division - drug effects Cell Line, Tumor Cell Proliferation - drug effects DNA Fragmentation - drug effects Female Humans MCF-7 Cells Naphthyridines - pharmacology Original
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