A Double‐Blind Randomized Controlled Trial To Study the Efficacy of Topiramate in a Civilian Sample of PTSD

SUMMARY Objective: To evaluate the efficacy and tolerability of topiramate in patients with posttraumatic stress disorder (PTSD). Method: We conducted a 12‐week double‐blind, randomized, placebo‐controlled study comparing topiramate to placebo. Men and women aged 18–62 years with diagnosis of PTSD a...

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Veröffentlicht in:	CNS neuroscience & therapeutics 2011-10, Vol.17 (5), p.305-310
Hauptverfasser:	Yeh, Mary S. L., Mari, Jair Jesus, Costa, Mariana Caddrobi Pupo, Andreoli, Sergio Baxter, Bressan, Rodrigo Affonseca, Mello, Marcelo Feijó
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aggression Ambulatory Care - methods Anticonvulsants Biological and medical sciences Cardiovascular system Central nervous system Clinical trials Clinician‐administered PTSD scale Depression Double-Blind Method Emotions Female Fructose - analogs & derivatives Fructose - therapeutic use Hospitals Humans Immunomodulators Inventories Male Medical sciences Memory Middle Aged Multiple sclerosis and variants. Guillain barré syndrome and other inflammatory polyneuropathies. Leukoencephalitis Nervous system Neurology Neuroprotective Agents - therapeutic use Pharmacology. Drug treatments Post-traumatic stress disorder Posttraumatic stress disorder Randomized controlled clinical trial Social interactions Stress Stress Disorders, Post-Traumatic - drug therapy Stress Disorders, Post-Traumatic - epidemiology Stress Disorders, Post-Traumatic - psychology Topiramate Trauma Treatment Outcome Vasodilator agents. Cerebral vasodilators
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