Rapid and Accurate Determination of Nanopore Ionic Current Using a Steric Exclusion Model

Nanopore sensing has emerged as a versatile approach to detection and identification of biomolecules. Presently, researchers rely on experience and intuition for choosing or modifying the nanopores to detect a target analyte. The field would greatly benefit from a computational method that could rel...

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Veröffentlicht in:	ACS sensors 2019-03, Vol.4 (3), p.634-644
Hauptverfasser:	Wilson, James, Sarthak, Kumar, Si, Wei, Gao, Luyu, Aksimentiev, Aleksei
Format:	Artikel
Sprache:	eng
Schlagworte:	DNA - chemistry DNA - metabolism Electric Conductivity Ion Transport Molecular Dynamics Simulation Nanopores Nucleosomes - metabolism Point Mutation Porins - genetics Porins - metabolism Time Factors
Online-Zugang:	Volltext
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