Methionine sulfoxide reductase B3 requires resolving cysteine residues for full activity and can act as a stereospecific methionine oxidase

The oxidation of methionine residues in proteins occurs during oxidative stress and can lead to an alteration in protein function. The enzyme methionine sulfoxide reductase (Msr) reverses this modification. Here, we characterise the mammalian enzyme Msr B3. There are two splice variants of this enzy...

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Veröffentlicht in:Biochemical journal 2018-02, Vol.475 (4), p.827-838
Hauptverfasser: Cao, Zhenbo, Mitchell, Lorna, Hsia, Oliver, Scarpa, Miriam, Caldwell, Stuart T, Alfred, Arina D, Gennaris, Alexandra, Collet, Jean-François, Hartley, Richard C, Bulleid, Neil J
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Sprache:eng
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