Adaptive Strategies of the Candidate Probiotic E. coli Nissle in the Mammalian Gut

Probiotics are living microorganisms that are increasingly used as gastrointestinal therapeutics by virtue of their innate or engineered genetic function. Unlike abiotic therapeutics, probiotics can replicate in their intended site, subjecting their genomes and therapeutic properties to natural sele...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Cell host & microbe 2019-04, Vol.25 (4), p.499-512.e8
Hauptverfasser:	Crook, Nathan, Ferreiro, Aura, Gasparrini, Andrew J., Pesesky, Mitchell W., Gibson, Molly K., Wang, Bin, Sun, Xiaoqing, Condiotte, Zevin, Dobrowolski, Stephen, Peterson, Daniel, Dantas, Gautam
Format:	Artikel
Sprache:	eng
Schlagworte:	Adaptation, Biological Animals Disease Models, Animal E. coli engineering Escherichia coli - growth & development Escherichia coli - metabolism evolution Gastrointestinal Agents - administration & dosage Gastrointestinal Tract - microbiology Metabolism Mice microbiome Mutation phenylketonuria Phenylketonurias - therapy probiotic Probiotics - administration & dosage Selection, Genetic
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!