DMP1 prevents osteocyte alterations, FGF23 elevation and left ventricular hypertrophy in mice with chronic kidney disease

During chronic kidney disease (CKD), alterations in bone and mineral metabolism include increased production of the hormone fibroblast growth factor 23 (FGF23) that may contribute to cardiovascular mortality. The osteocyte protein dentin matrix protein 1 (DMP1) reduces FGF23 and enhances bone minera...

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Veröffentlicht in:Bone Research 2019-04, Vol.7 (1), p.12-12, Article 12
Hauptverfasser: Dussold, Corey, Gerber, Claire, White, Samantha, Wang, Xueyan, Qi, Lixin, Francis, Connor, Capella, Maralee, Courbon, Guillaume, Wang, Jingya, Li, Chaoyuan, Feng, Jian Q., Isakova, Tamara, Wolf, Myles, David, Valentin, Martin, Aline
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Sprache:eng
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