Diverse reprogramming codes for neuronal identity

The transcriptional programs that establish neuronal identity evolved to produce the rich diversity of neuronal cell types that arise sequentially during development. Remarkably, transient expression of certain transcription factors can also endow non-neural cells with neuronal properties. The relat...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Nature (London) 2018-05, Vol.557 (7705), p.375-380
Hauptverfasser:	Tsunemoto, Rachel, Lee, Sohyon, Szűcs, Attila, Chubukov, Pavel, Sokolova, Irina, Blanchard, Joel W., Eade, Kevin T., Bruggemann, Jacob, Wu, Chunlei, Torkamani, Ali, Sanna, Pietro Paolo, Baldwin, Kristin K.
Format:	Artikel
Sprache:	eng
Schlagworte:	13/100 13/106 13/31 14/63 38/39 45/91 631/378/2571/2578 631/532/2128 9/74 Animals Bioinformatics Cell division Cellular Reprogramming - genetics Cloning DNA binding proteins Fibroblasts Fibroblasts - cytology Fibroblasts - metabolism Gene expression Gene Expression Profiling Gene Regulatory Networks Genes Genomes Humanities and Social Sciences Humans Induced Pluripotent Stem Cells - cytology Induced Pluripotent Stem Cells - metabolism Mice multidisciplinary Neural circuitry Neurons Neurons - cytology Neurons - drug effects Neurons - metabolism Neurophysiology Pharmacology Physiological aspects Science Science (multidisciplinary) Sequence Analysis, RNA Single-Cell Analysis Transcription (Genetics) Transcription factors Transcription Factors - metabolism Transcriptome - genetics
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!