Endogenous and Exogenous Modulation of Nrf2 Mediated Oxidative Stress Response in Bovine Granulosa Cells: Potential Implication for Ovarian Function

Nrf2 is a redox sensitive transcription factor regulating the expression of antioxidant genes as defense mechanism against various stressors. The aim of this study is to investigate the potential role of noncoding miRNAs as endogenous and quercetin as exogenous regulators of Nrf2 pathway in bovine g...

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Veröffentlicht in:	International journal of molecular sciences 2019-04, Vol.20 (7), p.1635
Hauptverfasser:	Khadrawy, Omar, Gebremedhn, Samuel, Salilew-Wondim, Dessie, Taqi, Mohamed Omar, Neuhoff, Christiane, Tholen, Ernst, Hoelker, Michael, Schellander, Karl, Tesfaye, Dawit
Format:	Artikel
Sprache:	eng
Schlagworte:	Antioxidants Apoptosis Binding sites Breast cancer Cell growth Cellular stress response DNA methylation Embryos Flavonoids Gametocytes Gene expression Granulosa cells Homeostasis MicroRNAs Mitochondria Oxidative stress Polycystic ovary syndrome Pregnancy Proteins Signal transduction Stress response Studies Transfection
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