Adjustment of the multi-biomarker disease activity score to account for age, sex and adiposity in patients with rheumatoid arthritis

Abstract Objective To develop and evaluate an adjusted score for the multi-biomarker disease activity (MBDA) test to account for the effects of age, sex and adiposity in patients with RA. Methods Two models were developed to adjust MBDA score for age, sex and adiposity, using either serum leptin con...

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Veröffentlicht in:	Rheumatology (Oxford, England) England), 2019-05, Vol.58 (5), p.874-883
Hauptverfasser:	Curtis, Jeffrey R, Flake, Darl D, Weinblatt, Michael E, Shadick, Nancy A, Østergaard, Mikkel, Hetland, Merete Lund, Brahe, Cecilie Heegaard, Hwang, Yong Gil, Furst, Daniel E, Strand, Vibeke, Etzel, Carol J, Pappas, Dimitrios A, Wang, Xingbin, Hwang, Ching Chang, Sasso, Eric H, Gutin, Alexander, Hitraya, Elena, Lanchbury, Jerry S
Format:	Artikel
Sprache:	eng
Schlagworte:	Adiposity Adult Age Factors Aged Arthritis, Rheumatoid - blood Arthritis, Rheumatoid - diagnosis Arthritis, Rheumatoid - physiopathology Biomarkers - analysis Body Mass Index Clinical Science Cohort Studies Disease Progression Female Humans Leptin - blood Male Middle Aged Predictive Value of Tests Radiography Reproducibility of Results Severity of Illness Index Sex Factors
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