Environmental enrichment and amantadine confer individual but nonadditive enhancements in motor and spatial learning after controlled cortical impact injury

•Amantadine (AMT) improved motor and cognitive performance after TBI.•Environmental enrichment (EE) improved motor and cognitive performance after TBI.•No additional benefits were observed with the combination of AMT and EE.•The lack of additive effects does not detract from the benefits of each the...

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Veröffentlicht in:Brain research 2019-07, Vol.1714, p.227-233
Hauptverfasser: Bleimeister, Isabel H., Wolff, Mia, Lam, Tracey R., Brooks, Derrick M., Patel, Reece, Cheng, Jeffrey P., Bondi, Corina O., Kline, Anthony E.
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Sprache:eng
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