Impact of bacterial probiotics on obesity, diabetes and non-alcoholic fatty liver disease related variables: a systematic review and meta-analysis of randomised controlled trials

ObjectiveTo systematically review the effect of oral intake of bacterial probiotics on 15 variables related to obesity, diabetes and non-alcoholic fatty liver disease.DesignSystematic review and meta-analysis.Data sourcesMedline, EMBASE and COCHRANE from 1990 to June 2018.Eligibility criteriaRandomi...

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Veröffentlicht in:	BMJ open 2019-03, Vol.9 (3), p.e017995-e017995
Hauptverfasser:	Koutnikova, Hana, Genser, Bernd, Monteiro-Sepulveda, Milena, Faurie, Jean-Michel, Rizkalla, Salwa, Schrezenmeir, Jürgen, Clément, Karine
Format:	Artikel
Sprache:	eng
Schlagworte:	Clinical trials Diabetes Diabetes Mellitus - metabolism Diabetes Mellitus - therapy Dietary Supplements Endocrinology and metabolism Evidence-based medicine Food and Nutrition Human health and pathology Humans Insulin resistance Life Sciences Liver diseases Meta-analysis Non-alcoholic Fatty Liver Disease - metabolism Non-alcoholic Fatty Liver Disease - therapy Nutrition and Metabolism Obesity Obesity - metabolism Obesity - therapy Probiotics Probiotics - pharmacology Randomized Controlled Trials as Topic Santé publique et épidémiologie Systematic review Treatment Outcome
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Beschreibung
Zusammenfassung:	ObjectiveTo systematically review the effect of oral intake of bacterial probiotics on 15 variables related to obesity, diabetes and non-alcoholic fatty liver disease.DesignSystematic review and meta-analysis.Data sourcesMedline, EMBASE and COCHRANE from 1990 to June 2018.Eligibility criteriaRandomised controlled trials (≥14 days) excluding hypercholesterolaemia, alcoholic liver disease, polycystic ovary syndrome and children
ISSN:	2044-6055 2044-6055
DOI:	10.1136/bmjopen-2017-017995