Intracranial Hemorrhage Following Thrombolytic Use for Stroke Caused by Infective Endocarditis
Background and Purpose Stroke is one of the most common neurological manifestations of infective endocarditis. The use of intravenous tissue plasminogen activator (t-PA) in the management of acute ischemic stroke is the accepted standard of practice. Current guidelines for intravenous (IV) t-PA ther...
Gespeichert in:
| Veröffentlicht in: | Neurocritical care 2010-02, Vol.12 (1), p.79-82 |
|---|---|
| Hauptverfasser: | , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 82 |
|---|---|
| container_issue | 1 |
| container_start_page | 79 |
| container_title | Neurocritical care |
| container_volume | 12 |
| creator | Bhuva, Parita Kuo, Sheng-Han Claude Hemphill, J. Lopez, George A. |
| description | Background and Purpose
Stroke is one of the most common neurological manifestations of infective endocarditis. The use of intravenous tissue plasminogen activator (t-PA) in the management of acute ischemic stroke is the accepted standard of practice.
Current guidelines for intravenous (IV) t-PA therapy in acute ischemic stroke do not exclude patients with infective endocarditis.
Summary of the Case
We present three patients who received IV t-PA for acute ischemic stroke in the setting of infective endocarditis and developed multifocal intracranial hemorrhage as a complication.
Conclusion
Infective endocarditis related strokes are associated with a higher risk of hemorrhagic complications and our experience suggests that IV t-PA use may potentiate that risk. |
| doi_str_mv | 10.1007/s12028-009-9253-5 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6474241</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>746275839</sourcerecordid><originalsourceid>FETCH-LOGICAL-c501t-51e153ad36940bab6fa2740f52573bcb61280b34283b7d90869b770d70d2fe4a3</originalsourceid><addsrcrecordid>eNp1kV1rFDEUhoMotlZ_gDcS8MKrqfnO5EaQpR8LBS_a3jYkmcxu6kxSk5nK_vtm2MVaQQgkcJ7z5hweAD5idIoRkl8LJoi0DUKqUYTThr8Cx5hz0SAl8OvlzXAjFKVH4F0p9wgRqSR_C46wEm0rMDkGd-s4ZeOyicEM8NKPKeet2Xh4noYh_Q5xA2-2OY02DbspOHhbPOxThtdTTj89XJm5-A7aHVzH3rspPHp4FrvkTO7CFMp78KY3Q_EfDvcJuD0_u1ldNlc_Ltar71eN4whPDccec2o6KhRD1ljRGyIZ6jnhklpn66gtspSRllrZKdQKZaVEXT2k98zQE_Btn_sw29F3zi9bDfohh9HknU4m6JeVGLZ6kx61YJIRhmvAl0NATr9mXyY9huL8MJjo01y0ZIJI3lJVyc__kPdpzrFup4lafFAuUKXwnnI5lZJ9_2cWjPQiT-_l6SpPL_I0rz2f_l7iueNgqwJkD5Raihufn7_-f-oTT2CloA</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2920283560</pqid></control><display><type>article</type><title>Intracranial Hemorrhage Following Thrombolytic Use for Stroke Caused by Infective Endocarditis</title><source>MEDLINE</source><source>ProQuest Central (Alumni Edition)</source><source>ProQuest Central UK/Ireland</source><source>SpringerLink Journals - AutoHoldings</source><source>ProQuest Central</source><creator>Bhuva, Parita ; Kuo, Sheng-Han ; Claude Hemphill, J. ; Lopez, George A.</creator><creatorcontrib>Bhuva, Parita ; Kuo, Sheng-Han ; Claude Hemphill, J. ; Lopez, George A.</creatorcontrib><description>Background and Purpose
Stroke is one of the most common neurological manifestations of infective endocarditis. The use of intravenous tissue plasminogen activator (t-PA) in the management of acute ischemic stroke is the accepted standard of practice.
Current guidelines for intravenous (IV) t-PA therapy in acute ischemic stroke do not exclude patients with infective endocarditis.
Summary of the Case
We present three patients who received IV t-PA for acute ischemic stroke in the setting of infective endocarditis and developed multifocal intracranial hemorrhage as a complication.
Conclusion
Infective endocarditis related strokes are associated with a higher risk of hemorrhagic complications and our experience suggests that IV t-PA use may potentiate that risk.</description><identifier>ISSN: 1541-6933</identifier><identifier>EISSN: 1556-0961</identifier><identifier>DOI: 10.1007/s12028-009-9253-5</identifier><identifier>PMID: 19688612</identifier><language>eng</language><publisher>New York: Humana Press Inc</publisher><subject>Aged ; Aneurysms ; Antibiotics ; Aphasia ; Blood ; Cerebral Angiography ; Cerebral Infarction - diagnosis ; Cerebral Infarction - drug therapy ; Cerebral Infarction - etiology ; Corynebacterium Infections - complications ; Councils ; Critical Care Medicine ; Drug use ; Endocarditis ; Endocarditis, Bacterial - complications ; Female ; Fibrinolytic Agents - adverse effects ; Fibrinolytic Agents - therapeutic use ; Hemorrhage ; Humans ; Hypertension ; Infusions, Intravenous ; Intensive ; Internal Medicine ; Intracranial Hemorrhages - chemically induced ; Intracranial Hemorrhages - diagnosis ; Ischemia ; Leukocytes ; Male ; Medicine ; Medicine & Public Health ; Middle Aged ; Neurology ; Patients ; Practical Pearl ; Streptococcal Infections - complications ; Stroke ; Subarachnoid Hemorrhage - chemically induced ; Subarachnoid Hemorrhage - diagnosis ; Thrombolytic Therapy - adverse effects ; Tissue Plasminogen Activator - adverse effects ; Tissue Plasminogen Activator - therapeutic use ; Tomography, X-Ray Computed ; Ultrasonic imaging ; Viridans Streptococci</subject><ispartof>Neurocritical care, 2010-02, Vol.12 (1), p.79-82</ispartof><rights>Humana Press Inc. 2009</rights><rights>Humana Press Inc. 2009.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c501t-51e153ad36940bab6fa2740f52573bcb61280b34283b7d90869b770d70d2fe4a3</citedby><cites>FETCH-LOGICAL-c501t-51e153ad36940bab6fa2740f52573bcb61280b34283b7d90869b770d70d2fe4a3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1007/s12028-009-9253-5$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://www.proquest.com/docview/2920283560?pq-origsite=primo$$EHTML$$P50$$Gproquest$$H</linktohtml><link.rule.ids>230,314,780,784,885,21388,21389,27924,27925,33530,33531,33744,33745,41488,42557,43659,43805,51319,64385,64387,64389,72469</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/19688612$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Bhuva, Parita</creatorcontrib><creatorcontrib>Kuo, Sheng-Han</creatorcontrib><creatorcontrib>Claude Hemphill, J.</creatorcontrib><creatorcontrib>Lopez, George A.</creatorcontrib><title>Intracranial Hemorrhage Following Thrombolytic Use for Stroke Caused by Infective Endocarditis</title><title>Neurocritical care</title><addtitle>Neurocrit Care</addtitle><addtitle>Neurocrit Care</addtitle><description>Background and Purpose
Stroke is one of the most common neurological manifestations of infective endocarditis. The use of intravenous tissue plasminogen activator (t-PA) in the management of acute ischemic stroke is the accepted standard of practice.
Current guidelines for intravenous (IV) t-PA therapy in acute ischemic stroke do not exclude patients with infective endocarditis.
Summary of the Case
We present three patients who received IV t-PA for acute ischemic stroke in the setting of infective endocarditis and developed multifocal intracranial hemorrhage as a complication.
Conclusion
Infective endocarditis related strokes are associated with a higher risk of hemorrhagic complications and our experience suggests that IV t-PA use may potentiate that risk.</description><subject>Aged</subject><subject>Aneurysms</subject><subject>Antibiotics</subject><subject>Aphasia</subject><subject>Blood</subject><subject>Cerebral Angiography</subject><subject>Cerebral Infarction - diagnosis</subject><subject>Cerebral Infarction - drug therapy</subject><subject>Cerebral Infarction - etiology</subject><subject>Corynebacterium Infections - complications</subject><subject>Councils</subject><subject>Critical Care Medicine</subject><subject>Drug use</subject><subject>Endocarditis</subject><subject>Endocarditis, Bacterial - complications</subject><subject>Female</subject><subject>Fibrinolytic Agents - adverse effects</subject><subject>Fibrinolytic Agents - therapeutic use</subject><subject>Hemorrhage</subject><subject>Humans</subject><subject>Hypertension</subject><subject>Infusions, Intravenous</subject><subject>Intensive</subject><subject>Internal Medicine</subject><subject>Intracranial Hemorrhages - chemically induced</subject><subject>Intracranial Hemorrhages - diagnosis</subject><subject>Ischemia</subject><subject>Leukocytes</subject><subject>Male</subject><subject>Medicine</subject><subject>Medicine & Public Health</subject><subject>Middle Aged</subject><subject>Neurology</subject><subject>Patients</subject><subject>Practical Pearl</subject><subject>Streptococcal Infections - complications</subject><subject>Stroke</subject><subject>Subarachnoid Hemorrhage - chemically induced</subject><subject>Subarachnoid Hemorrhage - diagnosis</subject><subject>Thrombolytic Therapy - adverse effects</subject><subject>Tissue Plasminogen Activator - adverse effects</subject><subject>Tissue Plasminogen Activator - therapeutic use</subject><subject>Tomography, X-Ray Computed</subject><subject>Ultrasonic imaging</subject><subject>Viridans Streptococci</subject><issn>1541-6933</issn><issn>1556-0961</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2010</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><recordid>eNp1kV1rFDEUhoMotlZ_gDcS8MKrqfnO5EaQpR8LBS_a3jYkmcxu6kxSk5nK_vtm2MVaQQgkcJ7z5hweAD5idIoRkl8LJoi0DUKqUYTThr8Cx5hz0SAl8OvlzXAjFKVH4F0p9wgRqSR_C46wEm0rMDkGd-s4ZeOyicEM8NKPKeet2Xh4noYh_Q5xA2-2OY02DbspOHhbPOxThtdTTj89XJm5-A7aHVzH3rspPHp4FrvkTO7CFMp78KY3Q_EfDvcJuD0_u1ldNlc_Ltar71eN4whPDccec2o6KhRD1ljRGyIZ6jnhklpn66gtspSRllrZKdQKZaVEXT2k98zQE_Btn_sw29F3zi9bDfohh9HknU4m6JeVGLZ6kx61YJIRhmvAl0NATr9mXyY9huL8MJjo01y0ZIJI3lJVyc__kPdpzrFup4lafFAuUKXwnnI5lZJ9_2cWjPQiT-_l6SpPL_I0rz2f_l7iueNgqwJkD5Raihufn7_-f-oTT2CloA</recordid><startdate>20100201</startdate><enddate>20100201</enddate><creator>Bhuva, Parita</creator><creator>Kuo, Sheng-Han</creator><creator>Claude Hemphill, J.</creator><creator>Lopez, George A.</creator><general>Humana Press Inc</general><general>Springer Nature B.V</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7RV</scope><scope>7X7</scope><scope>7XB</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9.</scope><scope>KB0</scope><scope>M0S</scope><scope>NAPCQ</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>7TK</scope><scope>5PM</scope></search><sort><creationdate>20100201</creationdate><title>Intracranial Hemorrhage Following Thrombolytic Use for Stroke Caused by Infective Endocarditis</title><author>Bhuva, Parita ; Kuo, Sheng-Han ; Claude Hemphill, J. ; Lopez, George A.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c501t-51e153ad36940bab6fa2740f52573bcb61280b34283b7d90869b770d70d2fe4a3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2010</creationdate><topic>Aged</topic><topic>Aneurysms</topic><topic>Antibiotics</topic><topic>Aphasia</topic><topic>Blood</topic><topic>Cerebral Angiography</topic><topic>Cerebral Infarction - diagnosis</topic><topic>Cerebral Infarction - drug therapy</topic><topic>Cerebral Infarction - etiology</topic><topic>Corynebacterium Infections - complications</topic><topic>Councils</topic><topic>Critical Care Medicine</topic><topic>Drug use</topic><topic>Endocarditis</topic><topic>Endocarditis, Bacterial - complications</topic><topic>Female</topic><topic>Fibrinolytic Agents - adverse effects</topic><topic>Fibrinolytic Agents - therapeutic use</topic><topic>Hemorrhage</topic><topic>Humans</topic><topic>Hypertension</topic><topic>Infusions, Intravenous</topic><topic>Intensive</topic><topic>Internal Medicine</topic><topic>Intracranial Hemorrhages - chemically induced</topic><topic>Intracranial Hemorrhages - diagnosis</topic><topic>Ischemia</topic><topic>Leukocytes</topic><topic>Male</topic><topic>Medicine</topic><topic>Medicine & Public Health</topic><topic>Middle Aged</topic><topic>Neurology</topic><topic>Patients</topic><topic>Practical Pearl</topic><topic>Streptococcal Infections - complications</topic><topic>Stroke</topic><topic>Subarachnoid Hemorrhage - chemically induced</topic><topic>Subarachnoid Hemorrhage - diagnosis</topic><topic>Thrombolytic Therapy - adverse effects</topic><topic>Tissue Plasminogen Activator - adverse effects</topic><topic>Tissue Plasminogen Activator - therapeutic use</topic><topic>Tomography, X-Ray Computed</topic><topic>Ultrasonic imaging</topic><topic>Viridans Streptococci</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Bhuva, Parita</creatorcontrib><creatorcontrib>Kuo, Sheng-Han</creatorcontrib><creatorcontrib>Claude Hemphill, J.</creatorcontrib><creatorcontrib>Lopez, George A.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Nursing & Allied Health Database</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Database (Alumni Edition)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Nursing & Allied Health Premium</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>Neurosciences Abstracts</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Neurocritical care</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Bhuva, Parita</au><au>Kuo, Sheng-Han</au><au>Claude Hemphill, J.</au><au>Lopez, George A.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Intracranial Hemorrhage Following Thrombolytic Use for Stroke Caused by Infective Endocarditis</atitle><jtitle>Neurocritical care</jtitle><stitle>Neurocrit Care</stitle><addtitle>Neurocrit Care</addtitle><date>2010-02-01</date><risdate>2010</risdate><volume>12</volume><issue>1</issue><spage>79</spage><epage>82</epage><pages>79-82</pages><issn>1541-6933</issn><eissn>1556-0961</eissn><abstract>Background and Purpose
Stroke is one of the most common neurological manifestations of infective endocarditis. The use of intravenous tissue plasminogen activator (t-PA) in the management of acute ischemic stroke is the accepted standard of practice.
Current guidelines for intravenous (IV) t-PA therapy in acute ischemic stroke do not exclude patients with infective endocarditis.
Summary of the Case
We present three patients who received IV t-PA for acute ischemic stroke in the setting of infective endocarditis and developed multifocal intracranial hemorrhage as a complication.
Conclusion
Infective endocarditis related strokes are associated with a higher risk of hemorrhagic complications and our experience suggests that IV t-PA use may potentiate that risk.</abstract><cop>New York</cop><pub>Humana Press Inc</pub><pmid>19688612</pmid><doi>10.1007/s12028-009-9253-5</doi><tpages>4</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1541-6933 |
| ispartof | Neurocritical care, 2010-02, Vol.12 (1), p.79-82 |
| issn | 1541-6933 1556-0961 |
| language | eng |
| recordid | cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6474241 |
| source | MEDLINE; ProQuest Central (Alumni Edition); ProQuest Central UK/Ireland; SpringerLink Journals - AutoHoldings; ProQuest Central |
| subjects | Aged Aneurysms Antibiotics Aphasia Blood Cerebral Angiography Cerebral Infarction - diagnosis Cerebral Infarction - drug therapy Cerebral Infarction - etiology Corynebacterium Infections - complications Councils Critical Care Medicine Drug use Endocarditis Endocarditis, Bacterial - complications Female Fibrinolytic Agents - adverse effects Fibrinolytic Agents - therapeutic use Hemorrhage Humans Hypertension Infusions, Intravenous Intensive Internal Medicine Intracranial Hemorrhages - chemically induced Intracranial Hemorrhages - diagnosis Ischemia Leukocytes Male Medicine Medicine & Public Health Middle Aged Neurology Patients Practical Pearl Streptococcal Infections - complications Stroke Subarachnoid Hemorrhage - chemically induced Subarachnoid Hemorrhage - diagnosis Thrombolytic Therapy - adverse effects Tissue Plasminogen Activator - adverse effects Tissue Plasminogen Activator - therapeutic use Tomography, X-Ray Computed Ultrasonic imaging Viridans Streptococci |
| title | Intracranial Hemorrhage Following Thrombolytic Use for Stroke Caused by Infective Endocarditis |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-05T08%3A16%3A20IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Intracranial%20Hemorrhage%20Following%20Thrombolytic%20Use%20for%20Stroke%20Caused%20by%20Infective%20Endocarditis&rft.jtitle=Neurocritical%20care&rft.au=Bhuva,%20Parita&rft.date=2010-02-01&rft.volume=12&rft.issue=1&rft.spage=79&rft.epage=82&rft.pages=79-82&rft.issn=1541-6933&rft.eissn=1556-0961&rft_id=info:doi/10.1007/s12028-009-9253-5&rft_dat=%3Cproquest_pubme%3E746275839%3C/proquest_pubme%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2920283560&rft_id=info:pmid/19688612&rfr_iscdi=true |