Obesity-Induced Changes in T-Cell Metabolism Are Associated With Impaired Memory T-Cell Response to Influenza and Are Not Reversed With Weight Loss

Obesity is an independent risk factor for increased influenza mortality and is associated with impaired memory T-cell response, resulting in increased risk of infection. In this study, we investigated if weight loss would restore memory T-cell response to influenza. Male C57BL/6J mice were fed eithe...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:The Journal of infectious diseases 2019-04, Vol.219 (10), p.1652-1661
Hauptverfasser: Rebeles, Jennifer, Green, William D, Alwarawrah, Yazan, Nichols, Amanda G, Eisner, William, Danzaki, Keiko, MacIver, Nancie J, Beck, Melinda A
Format: Artikel
Sprache:eng
Schlagworte:
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!