Regulation of estrogen signaling and breast cancer proliferation by an ubiquitin ligase TRIM56

Breast cancer ranks no. 1 in women cancer worldwide, while 60–70% are estrogen receptor alpha positive. The estrogen selective modulators, such as tamoxifen, become the effective drugs for controlling ER alpha breast cancer progression. However, tamoxifen resistance will develop during long-time tre...

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Veröffentlicht in:	Oncogenesis (New York, NY) NY), 2019-04, Vol.8 (5), p.30-30, Article 30
Hauptverfasser:	Xue, Min, Zhang, Kai, Mu, Kun, Xu, Juntao, Yang, Huijie, Liu, Yun, Wang, Beibei, Wang, Zhonghao, Li, Zhongbo, Kong, Qiong, Li, Xiumin, Wang, Hui, Zhu, Jian, Zhuang, Ting
Format:	Artikel
Sprache:	eng
Schlagworte:	13 13/106 13/109 13/89 13/95 14/63 631/67/1347 631/80/86/2363 Apoptosis Breast cancer Cell Biology Cytoplasm Endocrine therapy Estrogen receptors Human Genetics Internal Medicine Medicine Medicine & Public Health Oncology Tamoxifen Ubiquitin Ubiquitin-protein ligase Ubiquitination
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