Sphingosine-1-Phosphate Reduces Hemorrhagic Shock and Resuscitation-Induced Microvascular Leakage by Protecting Endothelial Mitochondrial Integrity

ABSTRACTExcessive microvascular permeability is a serious complication following hemorrhagic shock and resuscitation (HSR). S1P has been shown to ameliorate microvascular leakage in a model of combined alcohol intoxication and HSR. In the current study, we tested the hypothesis that S1P reduces HSR-...

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Veröffentlicht in:	Shock (Augusta, Ga.) Ga.), 2019-10, Vol.52 (4), p.423-433
Hauptverfasser:	Alves, Natascha G, Trujillo, Andrea N, Breslin, Jerome W, Yuan, Sarah Y
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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