Detection and Surveillance of Bladder Cancer Using Urine Tumor DNA

Current regimens for the detection and surveillance of bladder cancer are invasive and have suboptimal sensitivity. Here, we present a novel high-throughput sequencing (HTS) method for detection of urine tumor DNA (utDNA) called utDNA CAPP-Seq (uCAPP-Seq) and apply it to 67 healthy adults and 118 pa...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Cancer discovery 2019-04, Vol.9 (4), p.500-509
Hauptverfasser:	Dudley, Jonathan C, Schroers-Martin, Joseph, Lazzareschi, Daniel V, Shi, William Y, Chen, Simon B, Esfahani, Mohammad S, Trivedi, Dharati, Chabon, Jacob J, Chaudhuri, Aadel A, Stehr, Henning, Liu, Chih Long, Lim, Harumi, Costa, Helio A, Nabet, Barzin Y, Sin, Mandy L Y, Liao, Joseph C, Alizadeh, Ash A, Diehn, Maximilian
Format:	Artikel
Sprache:	eng
Schlagworte:	Biomarkers, Tumor - metabolism DNA, Neoplasm - urine Female Humans Male Urinary Bladder Neoplasms - diagnosis Urinary Bladder Neoplasms - urine
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!