Combined locoregional-immunotherapy for liver cancer

Locoregional therapies are commonly used to treat patients with hepatocellular carcinoma. It has been noted for many years that locoregional therapies may have additional systemic effects other than simple tumour elimination. Immunological “side effects” have been described in response to locoregion...

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Veröffentlicht in:	Journal of hepatology 2019-05, Vol.70 (5), p.999-1007
Hauptverfasser:	Greten, Tim F., Mauda-Havakuk, Michal, Heinrich, Bernd, Korangy, Firouzeh, Wood, Bradford J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animal models Animals Cell death Chemoembolization, Therapeutic CTLA-4 Antigen - antagonists & inhibitors Disease Models, Animal Hepatocellular carcinoma Humans Immune checkpoint Immune response Immunotherapy Immunotherapy - methods Liver cancer Liver Neoplasms - immunology Liver Neoplasms - pathology Liver Neoplasms - therapy Locoregional therapy Myeloid-Derived Suppressor Cells - physiology Radiofrequency Ablation T cell Tumors Tumour immunology
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